Microwave-Assisted Synthesis of Benzo[4,5]imidazo[1,2- a ]pyrimidines from β-Bromo-α,β-unsaturated Aldehydes and 2-Aminobenzimidazoles

Son Long Ho; Pham Duy Quang Dao; Chan Sik Cho

doi:10.1055/s-0036-1588834

Microwave-Assisted Synthesis of Benzo[4,5]imidazo[1,2- a ]pyrimidines from β-Bromo-α,β-unsaturated Aldehydes and 2-Aminobenzimidazoles

Son Long Ho
, Pham Duy Quang Dao
, Chan Sik Cho

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

β-Bromo-α,β-unsaturated aldehydes react with 2-aminobenzimidazoles by microwave irradiation in the presence of a base and magnesium sulfate to give the corresponding benzo[4,5]imidazo[1,2- a ]pyrimidines in moderate to good yields.

Original language	English
Pages (from-to)	1811-1815
Number of pages	5
Journal	Synlett
Volume	28
Issue number	14
DOIs	https://doi.org/10.1055/s-0036-1588834
State	Published - 1 Sep 2017

Keywords

aldehydes
coupling
cyclization
fused-ring systems
heterocycles

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10.1055/s-0036-1588834

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abstract = "β-Bromo-α,β-unsaturated aldehydes react with 2-aminobenzimidazoles by microwave irradiation in the presence of a base and magnesium sulfate to give the corresponding benzo[4,5]imidazo[1,2- a ]pyrimidines in moderate to good yields.",

keywords = "aldehydes, coupling, cyclization, fused-ring systems, heterocycles",

author = "Ho, \{Son Long\} and Dao, \{Pham Duy Quang\} and Cho, \{Chan Sik\}",

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AU - Ho, Son Long

AU - Dao, Pham Duy Quang

AU - Cho, Chan Sik

PY - 2017/9/1

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N2 - β-Bromo-α,β-unsaturated aldehydes react with 2-aminobenzimidazoles by microwave irradiation in the presence of a base and magnesium sulfate to give the corresponding benzo[4,5]imidazo[1,2- a ]pyrimidines in moderate to good yields.

AB - β-Bromo-α,β-unsaturated aldehydes react with 2-aminobenzimidazoles by microwave irradiation in the presence of a base and magnesium sulfate to give the corresponding benzo[4,5]imidazo[1,2- a ]pyrimidines in moderate to good yields.

KW - aldehydes

KW - coupling

KW - cyclization

KW - fused-ring systems

KW - heterocycles

UR - https://www.scopus.com/pages/publications/85019183529

U2 - 10.1055/s-0036-1588834

DO - 10.1055/s-0036-1588834

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AN - SCOPUS:85019183529

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SP - 1811

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JF - Synlett

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ER -

Microwave-Assisted Synthesis of Benzo[4,5]imidazo[1,2- a ]pyrimidines from β-Bromo-α,β-unsaturated Aldehydes and 2-Aminobenzimidazoles

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Keywords

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