Molecular consequences of PHOX2B missense, frameshift and alanine expansion mutations leading to autonomic dysfunction

Medicine and Dentistry

• Autonomic Dysfunction 100%
• Alanine 100%
• Transactivation 66%
• In Vitro 50%
• Missense Mutation 33%
• Frameshift Mutation 33%
• Disease 16%
• Neoplasm 16%
• Promoter Region 16%
• Immunofluorescence 16%
• Neurologic Disease 16%
• Autonomic Nervous System 16%
• Sympathetic Nervous System 16%

Biochemistry, Genetics and Molecular Biology

• Alanine 100%
• Missense 100%
• Transactivation 66%
• DNA Binding 50%
• Missense Mutation 33%
• Frameshift Mutation 33%
• Wild Type 16%
• Promoter Region 16%
• Immunofluorescence 16%
• Gel Filtration 16%

Neuroscience

• Dysautonomia 100%
• PHOX2B 100%
• Alanine 100%
• Transactivation 66%
• Frameshift Mutation 33%
• Sympathetic Nervous System 16%
• Protein Misfolding 16%
• Dopamine Beta Hydroxylase 16%