Molecular variability and genetic structure of the population of Soybean mosaic virus based on the analysis of complete genome sequences

Jang Kyun Seo; Kazusato Ohshima; Hyeok Geun Lee; Moonil Son; Hong Soo Choi; Su Heon Lee; Seong Han Sohn; Kook Hyung Kim

doi:10.1016/j.virol.2009.07.007

Molecular variability and genetic structure of the population of Soybean mosaic virus based on the analysis of complete genome sequences

Jang Kyun Seo, Kazusato Ohshima, Hyeok Geun Lee, Moonil Son, Hong Soo Choi, Su Heon Lee, Seong Han Sohn, Kook Hyung Kim

Department of Plant Medicine

Research output: Contribution to journal › Article › peer-review

102 Scopus citations

Abstract

The complete genomes of 30 Soybean mosaic virus (SMV) isolates and strains were sequenced in this study. Together with fourteen previously reported sequences, we analyzed the genetic structure of the SMV population. Analyses of genetic diversity showed that different genomic regions of SMV are under different evolutionary constraints and that there was no significant genetic differentiation between East Asian and North American populations of SMV. Phylogenetic analyses revealed a significant correlation between phylogeny of the cylindrical inclusion (CI) gene of SMV and SMV resistance gene 3 (Rsv3)-relating pathogenicity of SMV, suggesting CI might be a pathogenic determinant in Rsv3-mediated disease response. Interestingly, recombination analyses identified 19 'clear' recombination events in the SMV population. Furthermore, as several resistance-breaking strains were identified as recombinants, it appears that recombination might contribute to overcome host resistance in SMV-soybean pathosystem. Our finding suggests that recombination as well as mutation is an important evolutionary process in the genetic diversification of SMV population.

Original language	English
Pages (from-to)	91-103
Number of pages	13
Journal	Virology
Volume	393
Issue number	1
DOIs	https://doi.org/10.1016/j.virol.2009.07.007
State	Published - 10 Oct 2009

Keywords

Genetic structure
Genetic variation
Phylogenetic analysis
Recombination
SMV

Access to Document

10.1016/j.virol.2009.07.007

Cite this

@article{d8aba83c939349a2a75719b28299cdc1,

title = "Molecular variability and genetic structure of the population of Soybean mosaic virus based on the analysis of complete genome sequences",

abstract = "The complete genomes of 30 Soybean mosaic virus (SMV) isolates and strains were sequenced in this study. Together with fourteen previously reported sequences, we analyzed the genetic structure of the SMV population. Analyses of genetic diversity showed that different genomic regions of SMV are under different evolutionary constraints and that there was no significant genetic differentiation between East Asian and North American populations of SMV. Phylogenetic analyses revealed a significant correlation between phylogeny of the cylindrical inclusion (CI) gene of SMV and SMV resistance gene 3 (Rsv3)-relating pathogenicity of SMV, suggesting CI might be a pathogenic determinant in Rsv3-mediated disease response. Interestingly, recombination analyses identified 19 'clear' recombination events in the SMV population. Furthermore, as several resistance-breaking strains were identified as recombinants, it appears that recombination might contribute to overcome host resistance in SMV-soybean pathosystem. Our finding suggests that recombination as well as mutation is an important evolutionary process in the genetic diversification of SMV population.",

keywords = "Genetic structure, Genetic variation, Phylogenetic analysis, Recombination, SMV",

author = "Seo, {Jang Kyun} and Kazusato Ohshima and Lee, {Hyeok Geun} and Moonil Son and Choi, {Hong Soo} and Lee, {Su Heon} and Sohn, {Seong Han} and Kim, {Kook Hyung}",

year = "2009",

month = oct,

day = "10",

doi = "10.1016/j.virol.2009.07.007",

language = "English",

volume = "393",

pages = "91--103",

journal = "Virology",

issn = "0042-6822",

publisher = "Academic Press Inc.",

number = "1",

}

TY - JOUR

T1 - Molecular variability and genetic structure of the population of Soybean mosaic virus based on the analysis of complete genome sequences

AU - Seo, Jang Kyun

AU - Ohshima, Kazusato

AU - Lee, Hyeok Geun

AU - Son, Moonil

AU - Choi, Hong Soo

AU - Lee, Su Heon

AU - Sohn, Seong Han

AU - Kim, Kook Hyung

PY - 2009/10/10

Y1 - 2009/10/10

N2 - The complete genomes of 30 Soybean mosaic virus (SMV) isolates and strains were sequenced in this study. Together with fourteen previously reported sequences, we analyzed the genetic structure of the SMV population. Analyses of genetic diversity showed that different genomic regions of SMV are under different evolutionary constraints and that there was no significant genetic differentiation between East Asian and North American populations of SMV. Phylogenetic analyses revealed a significant correlation between phylogeny of the cylindrical inclusion (CI) gene of SMV and SMV resistance gene 3 (Rsv3)-relating pathogenicity of SMV, suggesting CI might be a pathogenic determinant in Rsv3-mediated disease response. Interestingly, recombination analyses identified 19 'clear' recombination events in the SMV population. Furthermore, as several resistance-breaking strains were identified as recombinants, it appears that recombination might contribute to overcome host resistance in SMV-soybean pathosystem. Our finding suggests that recombination as well as mutation is an important evolutionary process in the genetic diversification of SMV population.

AB - The complete genomes of 30 Soybean mosaic virus (SMV) isolates and strains were sequenced in this study. Together with fourteen previously reported sequences, we analyzed the genetic structure of the SMV population. Analyses of genetic diversity showed that different genomic regions of SMV are under different evolutionary constraints and that there was no significant genetic differentiation between East Asian and North American populations of SMV. Phylogenetic analyses revealed a significant correlation between phylogeny of the cylindrical inclusion (CI) gene of SMV and SMV resistance gene 3 (Rsv3)-relating pathogenicity of SMV, suggesting CI might be a pathogenic determinant in Rsv3-mediated disease response. Interestingly, recombination analyses identified 19 'clear' recombination events in the SMV population. Furthermore, as several resistance-breaking strains were identified as recombinants, it appears that recombination might contribute to overcome host resistance in SMV-soybean pathosystem. Our finding suggests that recombination as well as mutation is an important evolutionary process in the genetic diversification of SMV population.

KW - Genetic structure

KW - Genetic variation

KW - Phylogenetic analysis

KW - Recombination

KW - SMV

UR - http://www.scopus.com/inward/record.url?scp=70349240225&partnerID=8YFLogxK

U2 - 10.1016/j.virol.2009.07.007

DO - 10.1016/j.virol.2009.07.007

M3 - Article

C2 - 19716150

AN - SCOPUS:70349240225

SN - 0042-6822

VL - 393

SP - 91

EP - 103

JO - Virology

JF - Virology

IS - 1

ER -

Molecular variability and genetic structure of the population of Soybean mosaic virus based on the analysis of complete genome sequences

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this