Multiple simple bone cysts of the Jaws: Review of the literature and report of three cases

Seo Young An, Jae Seo Lee, Erika Benavides, Alireza Aminlari, Neville J. McDonald, Paul C. Edwards, Min Suk Heo, Hong In Shin, Jin Woo Park, Jae Kwang Jung, Karp Shik Choi, Chang Hyeon An

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Objectives This study contributes three well-documented cases of multiple simple bone cysts (SBCs) of the jaws and reviews previously published cases. Study Design A comprehensive literature search of multiple SBCs was conducted using the PubMed database. Synonyms of SBC were used as search key words in combination with "mandible or jaw," "bilateral, multiple, multifocal, atypical, and unusual." Results A total of 34 cases of multiple SBCs (including two asynchronous cases) were identified, including the three new cases reported here. Multiple SBCs primarily occurred in the second decade (52.9%) and bilaterally in the posterior mandible. Lesions demonstrated female predominance (1.8:1) and were frequently accompanied by bony expansion (44.1%) and a multilocular radiolucent appearance (20.6 %). Recurrence was reported in three patients (mean age: 39.3 years old). Conclusion Knowledge of the clinical and radiographic features of multiple SBCs is important in the diagnosis and management of this entity.

Original languageEnglish
Pages (from-to)e458-e469
JournalOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Issue number6
StatePublished - Jun 2014


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