Multiwalled carbon nanotubes grafted chitosan nanobiocomposite: A prosperous functional nanomaterials for glucose biosensor application

Palanisamy Gomathi, Min Kwan Kim, Jung Je Park, Dhanusuraman Ragupathy, Annamalai Rajendran, Soo Chool Lee, Jae Chang Kim, Sang Hak Lee, Han Do Ghim

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Multiwalled carbon nanotubes (MWNTs) grafted chitosan (CS) nanowire (NW) was prepared by phase separation method. Glucose oxidase (GOx) was sequentially immobilized into MWNT-CS-NW to obtain MWNT-CS-NW/GOx biosensor. Field emission scanning electron microscopy (FESEM) images of MWNT-CS-NW/GOx reveals the existence of MWNT and CS. Cyclic voltammetry and amperometry were used to evaluate the electrochemical determination of glucose. The MWNT-CS-NW/GOx biosensor shows an excellent performance for glucose at +0.34 V with a high sensitivity (5.03 μA/mM) and lower response time (3 s) in a wide concentration range of 1-10 mM (correlation coefficient of 0.9988). In addition, MWNT-CS-NW/GOx biosensor possesses better reproducibility, storage stability and there is negligible interference from other electroactive components.

Original languageEnglish
Pages (from-to)897-902
Number of pages6
JournalSensors and Actuators, B: Chemical
Volume155
Issue number2
DOIs
StatePublished - 20 Jul 2011

Keywords

  • Biocompatibility
  • Biosensor
  • Electroactivity
  • Glucose
  • MWNT
  • Nanowire

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