Abstract
Multiwalled carbon nanotubes (MWNTs) grafted chitosan (CS) nanowire (NW) was prepared by phase separation method. Glucose oxidase (GOx) was sequentially immobilized into MWNT-CS-NW to obtain MWNT-CS-NW/GOx biosensor. Field emission scanning electron microscopy (FESEM) images of MWNT-CS-NW/GOx reveals the existence of MWNT and CS. Cyclic voltammetry and amperometry were used to evaluate the electrochemical determination of glucose. The MWNT-CS-NW/GOx biosensor shows an excellent performance for glucose at +0.34 V with a high sensitivity (5.03 μA/mM) and lower response time (3 s) in a wide concentration range of 1-10 mM (correlation coefficient of 0.9988). In addition, MWNT-CS-NW/GOx biosensor possesses better reproducibility, storage stability and there is negligible interference from other electroactive components.
Original language | English |
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Pages (from-to) | 897-902 |
Number of pages | 6 |
Journal | Sensors and Actuators, B: Chemical |
Volume | 155 |
Issue number | 2 |
DOIs | |
State | Published - 20 Jul 2011 |
Keywords
- Biocompatibility
- Biosensor
- Electroactivity
- Glucose
- MWNT
- Nanowire