Nanotechnology: A Toolkit for Cell Behavior

Christopher O’Brien, Sung Yun Hann, Benjamin Holmes, Lijie Grace Zhang

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Tissue engineering seeks to effectively manipulate cellular populations to improve the function of damaged or diseased tissues and organs. Many techniques can affect cell behavior; however, in order to maintain desirable function, scientists and engineers design solutions that are as biomimetic as possible. True biomimeticity is very challenging without the incorporation of nanotechnology. Since cells in human tissues are surrounded by a three-dimensional (3D) hierarchical tissue extracellular matrix containing numerous nanocomponents, a revolutionary change in tissue engineering is to explore biomimetic nanobiomaterials and advanced 3D nano/microfabrication techniques for creating novel tissue constructs and regulating cell behavior. This chapter provides an overview of recent nanotechnology in tissue engineering applications. We will put special emphasis on integrating cutting-edge 3D nano/microfabrication techniques with nanobiomaterials for complex tissue and organ regeneration.

Original languageEnglish
Title of host publication3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine
PublisherElsevier
Pages3-32
Number of pages30
ISBN (Electronic)9780128245521
ISBN (Print)9780128245538
DOIs
StatePublished - 1 Jan 2022

Keywords

  • Cells
  • Nanobiomaterials
  • Nanofabrication
  • Nanotechnology
  • Scaffold
  • Tissue regeneration

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