Numerical analysis for magnetophoretic separation of blood cells in fluid and magnetic field

Myung Ki Baek; Hong Soon Choi; Ki Sik Lee; Il Han Park

doi:10.1109/TASC.2011.2174584

Numerical analysis for magnetophoretic separation of blood cells in fluid and magnetic field

Myung Ki Baek, Hong Soon Choi, Ki Sik Lee, Il Han Park

Department of Electrical Engineering

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

In this paper, the characteristics of blood cell motion are analysed by solving a coupled electromagnetic, fluid and particle dynamics problem. The forces acting on blood cells are obtained from magnetic field and fluid field distributions, both of which are numerically calculated by the finite element method. These force consist of the magnetophoretic force, drag force, buoyancy and gravity, these are driving terms in Newton's equation for the particle motion. We propose a numerical analysis procedure to solve the coupled problem, and a micro cell separation device without a micro fabricated structure is designed. The dynamic characteristics of the cell motion are simulated. The simulation results show the proposed numerical scheme to analyse the micro particle dynamics and also show the usefulness of the designed device.

Original language	English
Article number	6069544
Journal	IEEE Transactions on Applied Superconductivity
Volume	22
Issue number	3
DOIs	https://doi.org/10.1109/TASC.2011.2174584
State	Published - 2012

Keywords

Biomedical engineering
cell separation
coupled problem
magnetophoretic force
numerical analysis

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10.1109/TASC.2011.2174584

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title = "Numerical analysis for magnetophoretic separation of blood cells in fluid and magnetic field",

abstract = "In this paper, the characteristics of blood cell motion are analysed by solving a coupled electromagnetic, fluid and particle dynamics problem. The forces acting on blood cells are obtained from magnetic field and fluid field distributions, both of which are numerically calculated by the finite element method. These force consist of the magnetophoretic force, drag force, buoyancy and gravity, these are driving terms in Newton's equation for the particle motion. We propose a numerical analysis procedure to solve the coupled problem, and a micro cell separation device without a micro fabricated structure is designed. The dynamic characteristics of the cell motion are simulated. The simulation results show the proposed numerical scheme to analyse the micro particle dynamics and also show the usefulness of the designed device.",

keywords = "Biomedical engineering, cell separation, coupled problem, magnetophoretic force, numerical analysis",

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T1 - Numerical analysis for magnetophoretic separation of blood cells in fluid and magnetic field

AU - Baek, Myung Ki

AU - Choi, Hong Soon

AU - Lee, Ki Sik

AU - Park, Il Han

PY - 2012

Y1 - 2012

N2 - In this paper, the characteristics of blood cell motion are analysed by solving a coupled electromagnetic, fluid and particle dynamics problem. The forces acting on blood cells are obtained from magnetic field and fluid field distributions, both of which are numerically calculated by the finite element method. These force consist of the magnetophoretic force, drag force, buoyancy and gravity, these are driving terms in Newton's equation for the particle motion. We propose a numerical analysis procedure to solve the coupled problem, and a micro cell separation device without a micro fabricated structure is designed. The dynamic characteristics of the cell motion are simulated. The simulation results show the proposed numerical scheme to analyse the micro particle dynamics and also show the usefulness of the designed device.

AB - In this paper, the characteristics of blood cell motion are analysed by solving a coupled electromagnetic, fluid and particle dynamics problem. The forces acting on blood cells are obtained from magnetic field and fluid field distributions, both of which are numerically calculated by the finite element method. These force consist of the magnetophoretic force, drag force, buoyancy and gravity, these are driving terms in Newton's equation for the particle motion. We propose a numerical analysis procedure to solve the coupled problem, and a micro cell separation device without a micro fabricated structure is designed. The dynamic characteristics of the cell motion are simulated. The simulation results show the proposed numerical scheme to analyse the micro particle dynamics and also show the usefulness of the designed device.

KW - Biomedical engineering

KW - cell separation

KW - coupled problem

KW - magnetophoretic force

KW - numerical analysis

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JO - IEEE Transactions on Applied Superconductivity

JF - IEEE Transactions on Applied Superconductivity

IS - 3

M1 - 6069544

ER -

Numerical analysis for magnetophoretic separation of blood cells in fluid and magnetic field

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