Odorless isocyanide chemistry: An integrated microfluidic system for a multistep reaction sequence

Siddharth Sharma; Ram Awatar Maurya; Kyoung Ik Min; Guan Young Jeong; Dong Pyo Kim

doi:10.1002/anie.201303213

Odorless isocyanide chemistry: An integrated microfluidic system for a multistep reaction sequence

Siddharth Sharma
, Ram Awatar Maurya
, Kyoung Ik Min
, Guan Young Jeong
, Dong Pyo Kim

Department of Biomedical Convergence Science & Technology

Pohang University of Science and Technology
CSIR - Indian Institute of Chemical Technology

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Abstract

Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA=N,N-diisopropylethylamine.

Original language	English
Pages (from-to)	7564-7568
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	29
DOIs	https://doi.org/10.1002/anie.201303213
State	Published - 15 Jul 2013

Keywords

continuous flow
isocyanides
microreactors
multi-component reactions
organometallics

Access to Document

10.1002/anie.201303213

Cite this

@article{5895a07ee0f14bd788ba608c702a7b6f,

title = "Odorless isocyanide chemistry: An integrated microfluidic system for a multistep reaction sequence",

abstract = "Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA=N,N-diisopropylethylamine.",

keywords = "continuous flow, isocyanides, microreactors, multi-component reactions, organometallics",

author = "Siddharth Sharma and Maurya, \{Ram Awatar\} and Min, \{Kyoung Ik\} and Jeong, \{Guan Young\} and Kim, \{Dong Pyo\}",

year = "2013",

month = jul,

day = "15",

doi = "10.1002/anie.201303213",

language = "English",

volume = "52",

pages = "7564--7568",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "29",

}

TY - JOUR

T1 - Odorless isocyanide chemistry

T2 - An integrated microfluidic system for a multistep reaction sequence

AU - Sharma, Siddharth

AU - Maurya, Ram Awatar

AU - Min, Kyoung Ik

AU - Jeong, Guan Young

AU - Kim, Dong Pyo

PY - 2013/7/15

Y1 - 2013/7/15

N2 - Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA=N,N-diisopropylethylamine.

AB - Can't smell this: An integrated continuous-flow microfluidic setup enables in situ generation, extraction, separation, and reaction of foul-smelling isocyanides with little exposure to the surroundings. Isocyanides were generated by dehydration of the corresponding N-substituted formamides, and several representative isocyanide-based organic reactions were successfully performed. DIPEA=N,N-diisopropylethylamine.

KW - continuous flow

KW - isocyanides

KW - microreactors

KW - multi-component reactions

KW - organometallics

UR - https://www.scopus.com/pages/publications/84880084645

U2 - 10.1002/anie.201303213

DO - 10.1002/anie.201303213

M3 - Article

AN - SCOPUS:84880084645

SN - 1433-7851

VL - 52

SP - 7564

EP - 7568

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 29

ER -

Odorless isocyanide chemistry: An integrated microfluidic system for a multistep reaction sequence

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this