Palladium-catalyzed carbonylative cyclization of β-Bromo-α, β-unsaturated carboxylic acids leading to maleic anhydrides

Yeon Kyu Bae, Chan Sik Cho

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

β-Bromo-α,β-unsaturated carboxylic acids are carbonylatively cyclized under carbon monoxide pressure in acetic acid in the presence of a catalytic amount of a palladium catalyst along with a base to give the corresponding maleic anhydrides in high yields.

Original languageEnglish
Article numberST-2013-U0446-L
Pages (from-to)1848-1850
Number of pages3
JournalSynlett
Volume24
Issue number14
DOIs
StatePublished - 2013

Keywords

  • carbonylation
  • cyclization
  • heterocycles
  • homogeneous catalysis
  • palladium

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