Abstract
2-Bromobenzaldehyde is carbonylatively cyclized with primary amines under carbon monoxide pressure in DMF at 100 °C in the presence of a catalytic amount of a palladium catalyst to give the corresponding isoindolin-1-ones in moderate to high yields.
Original language | English |
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Pages (from-to) | 2097-2099 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 50 |
Issue number | 18 |
DOIs | |
State | Published - 6 May 2009 |
Keywords
- 2-Bromobenzaldehyde
- Carbonylative cyclization
- Isoindolin-1-ones
- Palladium catalyst
- Primary amines