Palladium-catalyzed carbonylative cyclization of 2-bromobenzaldehyde with primary amines leading to isoindolin-1-ones

Chan Sik Cho; Wen Xiu Ren

doi:10.1016/j.tetlet.2009.02.109

Palladium-catalyzed carbonylative cyclization of 2-bromobenzaldehyde with primary amines leading to isoindolin-1-ones

Chan Sik Cho
, Wen Xiu Ren

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

2-Bromobenzaldehyde is carbonylatively cyclized with primary amines under carbon monoxide pressure in DMF at 100 °C in the presence of a catalytic amount of a palladium catalyst to give the corresponding isoindolin-1-ones in moderate to high yields.

Original language	English
Pages (from-to)	2097-2099
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	18
DOIs	https://doi.org/10.1016/j.tetlet.2009.02.109
State	Published - 6 May 2009

Keywords

2-Bromobenzaldehyde
Carbonylative cyclization
Isoindolin-1-ones
Palladium catalyst
Primary amines

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10.1016/j.tetlet.2009.02.109

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title = "Palladium-catalyzed carbonylative cyclization of 2-bromobenzaldehyde with primary amines leading to isoindolin-1-ones",

abstract = "2-Bromobenzaldehyde is carbonylatively cyclized with primary amines under carbon monoxide pressure in DMF at 100 °C in the presence of a catalytic amount of a palladium catalyst to give the corresponding isoindolin-1-ones in moderate to high yields.",

keywords = "2-Bromobenzaldehyde, Carbonylative cyclization, Isoindolin-1-ones, Palladium catalyst, Primary amines",

author = "Cho, \{Chan Sik\} and Ren, \{Wen Xiu\}",

year = "2009",

month = may,

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doi = "10.1016/j.tetlet.2009.02.109",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - Palladium-catalyzed carbonylative cyclization of 2-bromobenzaldehyde with primary amines leading to isoindolin-1-ones

AU - Cho, Chan Sik

AU - Ren, Wen Xiu

PY - 2009/5/6

Y1 - 2009/5/6

N2 - 2-Bromobenzaldehyde is carbonylatively cyclized with primary amines under carbon monoxide pressure in DMF at 100 °C in the presence of a catalytic amount of a palladium catalyst to give the corresponding isoindolin-1-ones in moderate to high yields.

AB - 2-Bromobenzaldehyde is carbonylatively cyclized with primary amines under carbon monoxide pressure in DMF at 100 °C in the presence of a catalytic amount of a palladium catalyst to give the corresponding isoindolin-1-ones in moderate to high yields.

KW - 2-Bromobenzaldehyde

KW - Carbonylative cyclization

KW - Isoindolin-1-ones

KW - Palladium catalyst

KW - Primary amines

UR - https://www.scopus.com/pages/publications/62349111557

U2 - 10.1016/j.tetlet.2009.02.109

DO - 10.1016/j.tetlet.2009.02.109

M3 - Article

AN - SCOPUS:62349111557

SN - 0040-4039

VL - 50

SP - 2097

EP - 2099

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 18

ER -

Palladium-catalyzed carbonylative cyclization of 2-bromobenzaldehyde with primary amines leading to isoindolin-1-ones

Abstract

Keywords

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