Palladium-catalyzed diastereoselective synthesis of isoindolinones

C. S. Cho, D. Y. Chu, D. Y. Lee, S. C. Shim, T. J. Kim, W. T. Lim, N. H. Heo

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

2-Bromobenzaldehyde reacts diastereoselectively with chiral alkanolamines under carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride to afford the corresponding tricyclic isoindolinones in moderate to good yields.

Original languageEnglish
Pages (from-to)4141-4158
Number of pages18
JournalSynthetic Communications
Volume27
Issue number23
DOIs
StatePublished - 1997

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