Palladium-Catalyzed Synthesis of 3-(Alkylamino)isoindolin-1-ones by Carbonylative Cyclization of 2-Bromobenzaldehyde with Primary Amines

Chan Sik Cho; Li Hong Jiang; Dong Yub Lee; Sang Chul Shim; Hyung Soo Lee; Sung Dong Cho

doi:10.1002/jhet.5570340446

Palladium-Catalyzed Synthesis of 3-(Alkylamino)isoindolin-1-ones by Carbonylative Cyclization of 2-Bromobenzaldehyde with Primary Amines

Chan Sik Cho
, Li Hong Jiang
, Dong Yub Lee
, Sang Chul Shim
, Hyung Soo Lee
, Sung Dong Cho

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

2-Bromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3-(alkylamino)isoindolin-1-ones in good yields.

Original language	English
Pages (from-to)	1371-1374
Number of pages	4
Journal	Journal of Heterocyclic Chemistry
Volume	34
Issue number	4
DOIs	https://doi.org/10.1002/jhet.5570340446
State	Published - 1997

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title = "Palladium-Catalyzed Synthesis of 3-(Alkylamino)isoindolin-1-ones by Carbonylative Cyclization of 2-Bromobenzaldehyde with Primary Amines",

abstract = "2-Bromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3-(alkylamino)isoindolin-1-ones in good yields.",

author = "Cho, \{Chan Sik\} and Jiang, \{Li Hong\} and Lee, \{Dong Yub\} and Shim, \{Sang Chul\} and Lee, \{Hyung Soo\} and Cho, \{Sung Dong\}",

year = "1997",

doi = "10.1002/jhet.5570340446",

language = "English",

volume = "34",

pages = "1371--1374",

journal = "Journal of Heterocyclic Chemistry",

issn = "0022-152X",

publisher = "John Wiley and Sons Inc.",

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T1 - Palladium-Catalyzed Synthesis of 3-(Alkylamino)isoindolin-1-ones by Carbonylative Cyclization of 2-Bromobenzaldehyde with Primary Amines

AU - Cho, Chan Sik

AU - Jiang, Li Hong

AU - Lee, Dong Yub

AU - Shim, Sang Chul

AU - Lee, Hyung Soo

AU - Cho, Sung Dong

PY - 1997

Y1 - 1997

N2 - 2-Bromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3-(alkylamino)isoindolin-1-ones in good yields.

AB - 2-Bromobenzaldehyde reacts with an excess of primary amines under a carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3-(alkylamino)isoindolin-1-ones in good yields.

UR - https://www.scopus.com/pages/publications/0001316960

U2 - 10.1002/jhet.5570340446

DO - 10.1002/jhet.5570340446

M3 - Article

AN - SCOPUS:0001316960

SN - 0022-152X

VL - 34

SP - 1371

EP - 1374

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 4

ER -

Palladium-Catalyzed Synthesis of 3-(Alkylamino)isoindolin-1-ones by Carbonylative Cyclization of 2-Bromobenzaldehyde with Primary Amines

Abstract

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