Palladium-catalyzed three-component cyclization of 2-bromocyclohex-1-enecarboxylic acids with carbon monoxide and arylhydrazines leading to 2-anilinohydroisoindoline-1,3-diones

Il Chul Yoon; Chan Sik Cho

doi:10.1002/aoc.3274

Palladium-catalyzed three-component cyclization of 2-bromocyclohex-1-enecarboxylic acids with carbon monoxide and arylhydrazines leading to 2-anilinohydroisoindoline-1,3-diones

Il Chul Yoon
, Chan Sik Cho

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

2-Bromocyclohex-1-enecarboxylic acids are carbonylatively cyclized with arylhydrazines or their hydrochlorides in tetrahydrofuran at 120 °C under carbon monoxide pressure in the presence of a catalytic amount of PdCl₂ and 1,3-bis(diphenylphosphino)propane along with Et₃N to give 2-anilinohydroisoindoline-1,3-diones.

Original language	English
Pages (from-to)	226-230
Number of pages	5
Journal	Applied Organometallic Chemistry
Volume	29
Issue number	4
DOIs	https://doi.org/10.1002/aoc.3274
State	Published - Apr 2015

Keywords

2-anilinohydroisoindoline-1 3-diones
2-bromocyclohex-1-enecarboxylic acids
arylhydrazines
carbonylation and cyclization
palladium catalyst

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10.1002/aoc.3274

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title = "Palladium-catalyzed three-component cyclization of 2-bromocyclohex-1-enecarboxylic acids with carbon monoxide and arylhydrazines leading to 2-anilinohydroisoindoline-1,3-diones",

abstract = "2-Bromocyclohex-1-enecarboxylic acids are carbonylatively cyclized with arylhydrazines or their hydrochlorides in tetrahydrofuran at 120 °C under carbon monoxide pressure in the presence of a catalytic amount of PdCl2 and 1,3-bis(diphenylphosphino)propane along with Et3N to give 2-anilinohydroisoindoline-1,3-diones.",

keywords = "2-anilinohydroisoindoline-1 3-diones, 2-bromocyclohex-1-enecarboxylic acids, arylhydrazines, carbonylation and cyclization, palladium catalyst",

author = "Yoon, \{Il Chul\} and Cho, \{Chan Sik\}",

note = "Publisher Copyright: Copyright {\textcopyright} 2015 John Wiley \& Sons, Ltd.",

year = "2015",

month = apr,

doi = "10.1002/aoc.3274",

language = "English",

volume = "29",

pages = "226--230",

journal = "Applied Organometallic Chemistry",

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T1 - Palladium-catalyzed three-component cyclization of 2-bromocyclohex-1-enecarboxylic acids with carbon monoxide and arylhydrazines leading to 2-anilinohydroisoindoline-1,3-diones

AU - Yoon, Il Chul

AU - Cho, Chan Sik

PY - 2015/4

Y1 - 2015/4

N2 - 2-Bromocyclohex-1-enecarboxylic acids are carbonylatively cyclized with arylhydrazines or their hydrochlorides in tetrahydrofuran at 120 °C under carbon monoxide pressure in the presence of a catalytic amount of PdCl2 and 1,3-bis(diphenylphosphino)propane along with Et3N to give 2-anilinohydroisoindoline-1,3-diones.

AB - 2-Bromocyclohex-1-enecarboxylic acids are carbonylatively cyclized with arylhydrazines or their hydrochlorides in tetrahydrofuran at 120 °C under carbon monoxide pressure in the presence of a catalytic amount of PdCl2 and 1,3-bis(diphenylphosphino)propane along with Et3N to give 2-anilinohydroisoindoline-1,3-diones.

KW - 2-anilinohydroisoindoline-1 3-diones

KW - 2-bromocyclohex-1-enecarboxylic acids

KW - arylhydrazines

KW - carbonylation and cyclization

KW - palladium catalyst

UR - https://www.scopus.com/pages/publications/85027952998

U2 - 10.1002/aoc.3274

DO - 10.1002/aoc.3274

M3 - Article

AN - SCOPUS:85027952998

SN - 0268-2605

VL - 29

SP - 226

EP - 230

JO - Applied Organometallic Chemistry

JF - Applied Organometallic Chemistry

IS - 4

ER -

Palladium-catalyzed three-component cyclization of 2-bromocyclohex-1-enecarboxylic acids with carbon monoxide and arylhydrazines leading to 2-anilinohydroisoindoline-1,3-diones

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