Palladium-catalyzed three-component cyclization: Synthesis of hydroisoindol-1-ones from 2-bromocyclohex-1-enecarbaldehydes, anilines and carbon monoxide

Chan Sik Cho; Hyo Bo Kim; Sang Yeon Lee

doi:10.1016/j.jorganchem.2010.03.025

Palladium-catalyzed three-component cyclization: Synthesis of hydroisoindol-1-ones from 2-bromocyclohex-1-enecarbaldehydes, anilines and carbon monoxide

Chan Sik Cho, Hyo Bo Kim, Sang Yeon Lee

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Short survey › peer-review

30 Scopus citations

Abstract

2-Bromocyclohex-1-enecarbaldehydes react with anilines under carbon monoxide pressure in DMF at 60 °C in the presence of a catalytic amount of PdCl₂(PhCN)₂ to afford the corresponding hydroisoindol-1-ones in good yields.

Original language	English
Pages (from-to)	1744-1748
Number of pages	5
Journal	Journal of Organometallic Chemistry
Volume	695
Issue number	12-13
DOIs	https://doi.org/10.1016/j.jorganchem.2010.03.025
State	Published - 1 Jun 2010

Keywords

2-Bromocyclohex-1-enecarbaldehydes
Anilines
Carbonylation
Cyclization
Hydroisoindol-1-ones
Palladium catalyst

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10.1016/j.jorganchem.2010.03.025

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title = "Palladium-catalyzed three-component cyclization: Synthesis of hydroisoindol-1-ones from 2-bromocyclohex-1-enecarbaldehydes, anilines and carbon monoxide",

abstract = "2-Bromocyclohex-1-enecarbaldehydes react with anilines under carbon monoxide pressure in DMF at 60 °C in the presence of a catalytic amount of PdCl2(PhCN)2 to afford the corresponding hydroisoindol-1-ones in good yields.",

keywords = "2-Bromocyclohex-1-enecarbaldehydes, Anilines, Carbonylation, Cyclization, Hydroisoindol-1-ones, Palladium catalyst",

author = "Cho, {Chan Sik} and Kim, {Hyo Bo} and Lee, {Sang Yeon}",

year = "2010",

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doi = "10.1016/j.jorganchem.2010.03.025",

language = "English",

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T1 - Palladium-catalyzed three-component cyclization

T2 - Synthesis of hydroisoindol-1-ones from 2-bromocyclohex-1-enecarbaldehydes, anilines and carbon monoxide

AU - Cho, Chan Sik

AU - Kim, Hyo Bo

AU - Lee, Sang Yeon

PY - 2010/6/1

Y1 - 2010/6/1

N2 - 2-Bromocyclohex-1-enecarbaldehydes react with anilines under carbon monoxide pressure in DMF at 60 °C in the presence of a catalytic amount of PdCl2(PhCN)2 to afford the corresponding hydroisoindol-1-ones in good yields.

AB - 2-Bromocyclohex-1-enecarbaldehydes react with anilines under carbon monoxide pressure in DMF at 60 °C in the presence of a catalytic amount of PdCl2(PhCN)2 to afford the corresponding hydroisoindol-1-ones in good yields.

KW - 2-Bromocyclohex-1-enecarbaldehydes

KW - Anilines

KW - Carbonylation

KW - Cyclization

KW - Hydroisoindol-1-ones

KW - Palladium catalyst

UR - http://www.scopus.com/inward/record.url?scp=77954218575&partnerID=8YFLogxK

U2 - 10.1016/j.jorganchem.2010.03.025

DO - 10.1016/j.jorganchem.2010.03.025

M3 - Short survey

AN - SCOPUS:77954218575

SN - 0022-328X

VL - 695

SP - 1744

EP - 1748

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

IS - 12-13

ER -

Palladium-catalyzed three-component cyclization: Synthesis of hydroisoindol-1-ones from 2-bromocyclohex-1-enecarbaldehydes, anilines and carbon monoxide

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Keywords

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