TY - GEN
T1 - Paper microfluidic detection of salmonella using a smart phone
AU - Park, Tu San
AU - Li, Wenyue
AU - Yoon, Jeong Yeol
PY - 2012
Y1 - 2012
N2 - We describe a novel demonstration of latex immunoagglutination assay in a paper microfluidics format and subsequent Mie scatter detection using the smart phone's flash and digital camera as optical sensing platform. The background noise was eliminated through careful optimization of Mie scatter parameters: The diameter of latex beads, surfactant concentration, the angle of scatter detection, etc. The detection limit was 10 CFU/mL for Salmonella typhimurium using the paper microfluidics and smart phone. This method can be used for any field deployable assays (demonstrated for foodborne pathogens here; can be used for medical, veterinary, and environmental diagnostics) and is low-cost, easy-to-use, near-real-time and handheld.
AB - We describe a novel demonstration of latex immunoagglutination assay in a paper microfluidics format and subsequent Mie scatter detection using the smart phone's flash and digital camera as optical sensing platform. The background noise was eliminated through careful optimization of Mie scatter parameters: The diameter of latex beads, surfactant concentration, the angle of scatter detection, etc. The detection limit was 10 CFU/mL for Salmonella typhimurium using the paper microfluidics and smart phone. This method can be used for any field deployable assays (demonstrated for foodborne pathogens here; can be used for medical, veterinary, and environmental diagnostics) and is low-cost, easy-to-use, near-real-time and handheld.
KW - Latex immunoagglutination
KW - Mie scatter
KW - Paper microfluidics
KW - Salmonella typhimurium
UR - http://www.scopus.com/inward/record.url?scp=84901770080&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:84901770080
SN - 9780979806452
T3 - Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
SP - 2002
EP - 2004
BT - Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
PB - Chemical and Biological Microsystems Society
T2 - 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
Y2 - 28 October 2012 through 1 November 2012
ER -