TY - JOUR
T1 - Peroxidase-like activity of an azamacrocyclic Ni(II) complex
AU - Cho, Jang Hoon
AU - Kim, Sunghwan
AU - Lee, Hong In
N1 - Publisher Copyright:
© 2022 Korean Chemical Society, Seoul & Wiley-VCH GmbH
PY - 2022/3
Y1 - 2022/3
N2 - Peroxidase-like activity of an azamacrocyclic Ni(II) complex, [Ni(II)(DMDAC)]2+ (DMDAC = 1,8-dimethyl-1,3,6,8,10,13-hexaaza-cyclotetradecane = 1,8-dimethyl diazacyclam), was investigated by observing the oxidation of 2,2′-azinobis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) in the presence of H2O2. UV/Vis and electron paramagnetic resonance spectral changes obtained from the mixture solution of [Ni(II)(DMDAC)](ClO4)2, ABTS, and H2O2 indicated that both ABTS and its oxidized form, ABTS+•, were the substrates of the peroxidase-like activity of [Ni(II)(DMDAC)]2+. Current work and previously reported experimental and theoretical works on the peroxidase-like activity of azamacrocyclic Ni(II) complexes suggest that these kind of macrocyclic Ni(II) complexes can generally exhibit peroxidase-like activity in aqueous solution and the catalytic cycle proceeds through the heterolytic cleavage of the O–OH bond in a Ni(II)-hydroperoxo species.
AB - Peroxidase-like activity of an azamacrocyclic Ni(II) complex, [Ni(II)(DMDAC)]2+ (DMDAC = 1,8-dimethyl-1,3,6,8,10,13-hexaaza-cyclotetradecane = 1,8-dimethyl diazacyclam), was investigated by observing the oxidation of 2,2′-azinobis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) in the presence of H2O2. UV/Vis and electron paramagnetic resonance spectral changes obtained from the mixture solution of [Ni(II)(DMDAC)](ClO4)2, ABTS, and H2O2 indicated that both ABTS and its oxidized form, ABTS+•, were the substrates of the peroxidase-like activity of [Ni(II)(DMDAC)]2+. Current work and previously reported experimental and theoretical works on the peroxidase-like activity of azamacrocyclic Ni(II) complexes suggest that these kind of macrocyclic Ni(II) complexes can generally exhibit peroxidase-like activity in aqueous solution and the catalytic cycle proceeds through the heterolytic cleavage of the O–OH bond in a Ni(II)-hydroperoxo species.
KW - azamacrocyclic Ni(II) complex
KW - Ni-oxo complex
KW - peroxidase activity
UR - http://www.scopus.com/inward/record.url?scp=85123203021&partnerID=8YFLogxK
U2 - 10.1002/bkcs.12493
DO - 10.1002/bkcs.12493
M3 - Article
AN - SCOPUS:85123203021
SN - 0253-2964
VL - 43
SP - 417
EP - 420
JO - Bulletin of the Korean Chemical Society
JF - Bulletin of the Korean Chemical Society
IS - 3
ER -