Peroxidase-like activity of an azamacrocyclic Ni(II) complex

Jang Hoon Cho, Sunghwan Kim, Hong In Lee

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Peroxidase-like activity of an azamacrocyclic Ni(II) complex, [Ni(II)(DMDAC)]2+ (DMDAC = 1,8-dimethyl-1,3,6,8,10,13-hexaaza-cyclotetradecane = 1,8-dimethyl diazacyclam), was investigated by observing the oxidation of 2,2′-azinobis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) in the presence of H2O2. UV/Vis and electron paramagnetic resonance spectral changes obtained from the mixture solution of [Ni(II)(DMDAC)](ClO4)2, ABTS, and H2O2 indicated that both ABTS and its oxidized form, ABTS+•, were the substrates of the peroxidase-like activity of [Ni(II)(DMDAC)]2+. Current work and previously reported experimental and theoretical works on the peroxidase-like activity of azamacrocyclic Ni(II) complexes suggest that these kind of macrocyclic Ni(II) complexes can generally exhibit peroxidase-like activity in aqueous solution and the catalytic cycle proceeds through the heterolytic cleavage of the O–OH bond in a Ni(II)-hydroperoxo species.

Original languageEnglish
Pages (from-to)417-420
Number of pages4
JournalBulletin of the Korean Chemical Society
Volume43
Issue number3
DOIs
StatePublished - Mar 2022

Keywords

  • azamacrocyclic Ni(II) complex
  • Ni-oxo complex
  • peroxidase activity

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