Phellinus baumii inhibits immediate-type allergic reactions

Tae Yong Shin; Hye Young Shin; Sang Hyun Kim; Dae Keun Kim; Byeong Suk Chae; Chan Ho Oh; Moon Gu Cho; Suk Heung Oh; Jong Hwa Kim; Tae Kyoo Lee; Jeong Suk Park; Sang Yong Kim

Phellinus baumii inhibits immediate-type allergic reactions

Tae Yong Shin, Hye Young Shin, Sang Hyun Kim, Dae Keun Kim, Byeong Suk Chae, Chan Ho Oh, Moon Gu Cho, Suk Heung Oh, Jong Hwa Kim, Tae Kyoo Lee, Jeong Suk Park, Sang Yong Kim

Department of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.

Original language	English
Pages (from-to)	232-236
Number of pages	5
Journal	Natural Product Sciences
Volume	12
Issue number	4
State	Published - Dec 2006

Keywords

Allergic reaction
Interleukin-6
Mast cells
Phellinus baumii
Tumor necrosis factor-α

Cite this

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title = "Phellinus baumii inhibits immediate-type allergic reactions",

abstract = "In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.",

keywords = "Allergic reaction, Interleukin-6, Mast cells, Phellinus baumii, Tumor necrosis factor-α",

author = "Shin, {Tae Yong} and Shin, {Hye Young} and Kim, {Sang Hyun} and Kim, {Dae Keun} and Chae, {Byeong Suk} and Oh, {Chan Ho} and Cho, {Moon Gu} and Oh, {Suk Heung} and Kim, {Jong Hwa} and Lee, {Tae Kyoo} and Park, {Jeong Suk} and Kim, {Sang Yong}",

year = "2006",

month = dec,

language = "English",

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pages = "232--236",

journal = "Natural Product Sciences",

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T1 - Phellinus baumii inhibits immediate-type allergic reactions

AU - Shin, Tae Yong

AU - Shin, Hye Young

AU - Kim, Sang Hyun

AU - Kim, Dae Keun

AU - Chae, Byeong Suk

AU - Oh, Chan Ho

AU - Cho, Moon Gu

AU - Oh, Suk Heung

AU - Kim, Jong Hwa

AU - Lee, Tae Kyoo

AU - Park, Jeong Suk

AU - Kim, Sang Yong

PY - 2006/12

Y1 - 2006/12

N2 - In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.

AB - In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.

KW - Allergic reaction

KW - Interleukin-6

KW - Mast cells

KW - Phellinus baumii

KW - Tumor necrosis factor-α

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M3 - Article

AN - SCOPUS:33846415814

SN - 1226-3907

VL - 12

SP - 232

EP - 236

JO - Natural Product Sciences

JF - Natural Product Sciences

IS - 4

ER -

Phellinus baumii inhibits immediate-type allergic reactions

Abstract

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