Phellinus baumii inhibits immediate-type allergic reactions

Tae Yong Shin; Hye Young Shin; Sang Hyun Kim; Dae Keun Kim; Byeong Suk Chae; Chan Ho Oh; Moon Gu Cho; Suk Heung Oh; Jong Hwa Kim; Tae Kyoo Lee; Jeong Suk Park; Sang Yong Kim

Phellinus baumii inhibits immediate-type allergic reactions

Tae Yong Shin
, Hye Young Shin
, Sang Hyun Kim
, Dae Keun Kim
, Byeong Suk Chae
, Chan Ho Oh
, Moon Gu Cho
, Suk Heung Oh
, Jong Hwa Kim
, Tae Kyoo Lee
, Jeong Suk Park
, Sang Yong Kim

Department of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.

Original language	English
Pages (from-to)	232-236
Number of pages	5
Journal	Natural Product Sciences
Volume	12
Issue number	4
State	Published - Dec 2006

Keywords

Allergic reaction
Interleukin-6
Mast cells
Phellinus baumii
Tumor necrosis factor-α

Cite this

@article{418cc92195bc419ab58179d8a81dae38,

title = "Phellinus baumii inhibits immediate-type allergic reactions",

abstract = "In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.",

keywords = "Allergic reaction, Interleukin-6, Mast cells, Phellinus baumii, Tumor necrosis factor-α",

author = "Shin, \{Tae Yong\} and Shin, \{Hye Young\} and Kim, \{Sang Hyun\} and Kim, \{Dae Keun\} and Chae, \{Byeong Suk\} and Oh, \{Chan Ho\} and Cho, \{Moon Gu\} and Oh, \{Suk Heung\} and Kim, \{Jong Hwa\} and Lee, \{Tae Kyoo\} and Park, \{Jeong Suk\} and Kim, \{Sang Yong\}",

year = "2006",

month = dec,

language = "English",

volume = "12",

pages = "232--236",

journal = "Natural Product Sciences",

issn = "1226-3907",

publisher = "Korean Society of Pharmacognosy",

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TY - JOUR

T1 - Phellinus baumii inhibits immediate-type allergic reactions

AU - Shin, Tae Yong

AU - Shin, Hye Young

AU - Kim, Sang Hyun

AU - Kim, Dae Keun

AU - Chae, Byeong Suk

AU - Oh, Chan Ho

AU - Cho, Moon Gu

AU - Oh, Suk Heung

AU - Kim, Jong Hwa

AU - Lee, Tae Kyoo

AU - Park, Jeong Suk

AU - Kim, Sang Yong

PY - 2006/12

Y1 - 2006/12

N2 - In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.

AB - In this study, we investigated the effect of Phellinus baumii (PB) on immediate-type allergic reaction and inflammatory cytokine secretion. PB inhibited compound 48/80-induced systemic reactions in mice. PB inhibited compound 48/80-induced plasma histamine release. In addition, PB also inhibited the immunoglobulin (Ig) E-mediated local allergic reaction. Furthermore, PB decreased the phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated tumor necrosis factor-α and interleukin-6 secretion in human mast cells. These results indicate that PB may be beneficial in the treatment of immediate-type allergic reactions.

KW - Allergic reaction

KW - Interleukin-6

KW - Mast cells

KW - Phellinus baumii

KW - Tumor necrosis factor-α

UR - https://www.scopus.com/pages/publications/33846415814

M3 - Article

AN - SCOPUS:33846415814

SN - 1226-3907

VL - 12

SP - 232

EP - 236

JO - Natural Product Sciences

JF - Natural Product Sciences

IS - 4

ER -

Phellinus baumii inhibits immediate-type allergic reactions

Abstract

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