Phenolic compounds from the flowers of coreopsis lanceolata

Hyoung Geun Kim; Hyun Ji Oh; Jung Hwan Ko; Young Sung Jung; Seon Min Oh; Yeong Geun Lee; Dae Ok Kim; Dae Young Lee; Nam In Baek

doi:10.3839/jabc.2019.044

Phenolic compounds from the flowers of coreopsis lanceolata

Hyoung Geun Kim, Hyun Ji Oh, Jung Hwan Ko, Young Sung Jung, Seon Min Oh, Yeong Geun Lee, Dae Ok Kim, Dae Young Lee, Nam In Baek

School of Life Science and Biotechnology

Kyung Hee University

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The flowers of Coreopsis lanceolata were extracted with 80% aqueous MeOH and the concentrates were partitioned into EtOAc, n-BuOH, and H₂O fractions. The repeated silica gel (SiO₂) and octadecyl silica gel column chromatographies for the EtOAc fraction led to isolation of one flavonol and one benzoyl compounds. The chemical structures of the compounds were respectively determined as melanoxetin (1) and protocatechuic acid methyl ester (2) based on spectroscopic analyses including NMR, IR, and MS. These two compounds were isolated for the first time from C. lanceolata flowers in this study. All fractions and the isolated compounds were evaluated for 2,2-diphenyl-1picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical scavenging activities.

Original language	English
Pages (from-to)	323-326
Number of pages	4
Journal	Journal of Applied Biological Chemistry
Volume	62
Issue number	4
DOIs	https://doi.org/10.3839/jabc.2019.044
State	Published - 2019

Keywords

Antioxidant
Benzoic acid
Coreopsis lanceolata
Flavonol
NMR

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title = "Phenolic compounds from the flowers of coreopsis lanceolata",

abstract = "The flowers of Coreopsis lanceolata were extracted with 80% aqueous MeOH and the concentrates were partitioned into EtOAc, n-BuOH, and H2O fractions. The repeated silica gel (SiO2) and octadecyl silica gel column chromatographies for the EtOAc fraction led to isolation of one flavonol and one benzoyl compounds. The chemical structures of the compounds were respectively determined as melanoxetin (1) and protocatechuic acid methyl ester (2) based on spectroscopic analyses including NMR, IR, and MS. These two compounds were isolated for the first time from C. lanceolata flowers in this study. All fractions and the isolated compounds were evaluated for 2,2-diphenyl-1picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical scavenging activities.",

keywords = "Antioxidant, Benzoic acid, Coreopsis lanceolata, Flavonol, NMR",

author = "Kim, {Hyoung Geun} and Oh, {Hyun Ji} and Ko, {Jung Hwan} and Jung, {Young Sung} and Oh, {Seon Min} and Lee, {Yeong Geun} and Kim, {Dae Ok} and Lee, {Dae Young} and Baek, {Nam In}",

note = "Publisher Copyright: {\textcopyright} The Korean Society for Applied Biological Chemistry 2019.",

year = "2019",

doi = "10.3839/jabc.2019.044",

language = "English",

volume = "62",

pages = "323--326",

journal = "Journal of Applied Biological Chemistry",

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T1 - Phenolic compounds from the flowers of coreopsis lanceolata

AU - Kim, Hyoung Geun

AU - Oh, Hyun Ji

AU - Ko, Jung Hwan

AU - Jung, Young Sung

AU - Oh, Seon Min

AU - Lee, Yeong Geun

AU - Kim, Dae Ok

AU - Lee, Dae Young

AU - Baek, Nam In

N1 - Publisher Copyright: © The Korean Society for Applied Biological Chemistry 2019.

PY - 2019

Y1 - 2019

N2 - The flowers of Coreopsis lanceolata were extracted with 80% aqueous MeOH and the concentrates were partitioned into EtOAc, n-BuOH, and H2O fractions. The repeated silica gel (SiO2) and octadecyl silica gel column chromatographies for the EtOAc fraction led to isolation of one flavonol and one benzoyl compounds. The chemical structures of the compounds were respectively determined as melanoxetin (1) and protocatechuic acid methyl ester (2) based on spectroscopic analyses including NMR, IR, and MS. These two compounds were isolated for the first time from C. lanceolata flowers in this study. All fractions and the isolated compounds were evaluated for 2,2-diphenyl-1picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical scavenging activities.

AB - The flowers of Coreopsis lanceolata were extracted with 80% aqueous MeOH and the concentrates were partitioned into EtOAc, n-BuOH, and H2O fractions. The repeated silica gel (SiO2) and octadecyl silica gel column chromatographies for the EtOAc fraction led to isolation of one flavonol and one benzoyl compounds. The chemical structures of the compounds were respectively determined as melanoxetin (1) and protocatechuic acid methyl ester (2) based on spectroscopic analyses including NMR, IR, and MS. These two compounds were isolated for the first time from C. lanceolata flowers in this study. All fractions and the isolated compounds were evaluated for 2,2-diphenyl-1picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid radical scavenging activities.

KW - Antioxidant

KW - Benzoic acid

KW - Coreopsis lanceolata

KW - Flavonol

KW - NMR

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U2 - 10.3839/jabc.2019.044

DO - 10.3839/jabc.2019.044

M3 - Article

AN - SCOPUS:85077089270

SN - 1976-0442

VL - 62

SP - 323

EP - 326

JO - Journal of Applied Biological Chemistry

JF - Journal of Applied Biological Chemistry

IS - 4

ER -

Phenolic compounds from the flowers of coreopsis lanceolata

Abstract

Keywords

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