Preparation and Characterization of Cyclodextrin Polymer and Its High-Performance Liquid-Chromatography Stationary Phase

Kwang Pill Lee; Seong Ho Choi; Eun Nyoung Ryu; Jae Jeong Ryoo; Jung Hag Park; Yongseong Kim; Myung Ho Hyun

doi:10.2116/analsci.18.31

Preparation and Characterization of Cyclodextrin Polymer and Its High-Performance Liquid-Chromatography Stationary Phase

Kwang Pill Lee, Seong Ho Choi, Eun Nyoung Ryu, Jae Jeong Ryoo, Jung Hag Park, Yongseong Kim, Myung Ho Hyun

Department of Chemical Science Education

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Cyclodextrin (CD) polymers were synthesized from the reaction of native CDs with a hexamethylene diisocyanate (HDI) compound in a dried DMF solution. The obtained CD polymer contained a range of 8 - 14% N due to HDI by elemental analysis. The physical and chemical properties of the CD polymers were characterized by IR, solid state ¹³C NMR, TGA, and DSC, respectively. An HPLC column was prepared using the CD polymer with a carbamate linker by a slurry method. Separation of the phenol isomers was conducted using the CD polymer stationary phase and CD by HPLC. Furthermore, an inclusion complex of the phenol isomer was studied by FT-Raman spectroscopy. From the HPLC and FT-Raman results, inclusion phenomena of o-, m-, and p-nitrophenol onto CD and CD polymers were analyzed.

Original language	English
Pages (from-to)	31-34
Number of pages	4
Journal	Analytical Sciences
Volume	18
Issue number	1
DOIs	https://doi.org/10.2116/analsci.18.31
State	Published - 2002

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abstract = "Cyclodextrin (CD) polymers were synthesized from the reaction of native CDs with a hexamethylene diisocyanate (HDI) compound in a dried DMF solution. The obtained CD polymer contained a range of 8 - 14% N due to HDI by elemental analysis. The physical and chemical properties of the CD polymers were characterized by IR, solid state 13C NMR, TGA, and DSC, respectively. An HPLC column was prepared using the CD polymer with a carbamate linker by a slurry method. Separation of the phenol isomers was conducted using the CD polymer stationary phase and CD by HPLC. Furthermore, an inclusion complex of the phenol isomer was studied by FT-Raman spectroscopy. From the HPLC and FT-Raman results, inclusion phenomena of o-, m-, and p-nitrophenol onto CD and CD polymers were analyzed.",

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T1 - Preparation and Characterization of Cyclodextrin Polymer and Its High-Performance Liquid-Chromatography Stationary Phase

AU - Lee, Kwang Pill

AU - Choi, Seong Ho

AU - Ryu, Eun Nyoung

AU - Ryoo, Jae Jeong

AU - Park, Jung Hag

AU - Kim, Yongseong

AU - Hyun, Myung Ho

PY - 2002

Y1 - 2002

N2 - Cyclodextrin (CD) polymers were synthesized from the reaction of native CDs with a hexamethylene diisocyanate (HDI) compound in a dried DMF solution. The obtained CD polymer contained a range of 8 - 14% N due to HDI by elemental analysis. The physical and chemical properties of the CD polymers were characterized by IR, solid state 13C NMR, TGA, and DSC, respectively. An HPLC column was prepared using the CD polymer with a carbamate linker by a slurry method. Separation of the phenol isomers was conducted using the CD polymer stationary phase and CD by HPLC. Furthermore, an inclusion complex of the phenol isomer was studied by FT-Raman spectroscopy. From the HPLC and FT-Raman results, inclusion phenomena of o-, m-, and p-nitrophenol onto CD and CD polymers were analyzed.

AB - Cyclodextrin (CD) polymers were synthesized from the reaction of native CDs with a hexamethylene diisocyanate (HDI) compound in a dried DMF solution. The obtained CD polymer contained a range of 8 - 14% N due to HDI by elemental analysis. The physical and chemical properties of the CD polymers were characterized by IR, solid state 13C NMR, TGA, and DSC, respectively. An HPLC column was prepared using the CD polymer with a carbamate linker by a slurry method. Separation of the phenol isomers was conducted using the CD polymer stationary phase and CD by HPLC. Furthermore, an inclusion complex of the phenol isomer was studied by FT-Raman spectroscopy. From the HPLC and FT-Raman results, inclusion phenomena of o-, m-, and p-nitrophenol onto CD and CD polymers were analyzed.

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Preparation and Characterization of Cyclodextrin Polymer and Its High-Performance Liquid-Chromatography Stationary Phase

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