Abstract
The prevalence and characterization of plasmid-mediated quinolone resistance (PMQR) determinants in ciprofloxacin-resistant Escherichia coli isolated from a Korean commercial layer farm were studied. A total of 45 ciprofloxacin-resistant E. coli isolates were recovered and all isolates were multidrug-resistant. Eight isolates have the PMQR genes aac(6')-Ib-cr, qnrS1, and qnrB4, and seven isolates exhibited double amino acid exchange at both gyrA and parC, and have high fluoroquinolone minimum inhibitory concentrations. Five transconjugants demonstrated transferability of PMQR and β-lactamase genes and similar antimicrobial resistance. Because PMQR genes in isolates from commercial layer chickens could enter the food supply and directly affect humans, control of ciprofloxacin resistance is needed.
| Original language | English |
|---|---|
| Pages (from-to) | 1180-1183 |
| Number of pages | 4 |
| Journal | Journal of Microbiology and Biotechnology |
| Volume | 30 |
| Issue number | 8 |
| DOIs | |
| State | Published - 28 Aug 2020 |
Keywords
- Antimicrobial resistance
- Commercial layer chicken
- Escherichia coli
- Fluoroquinolones
- Plasmid-mediated quinolone resistance