Prevalence of severe fever with thrombocytopenia syndrome virus in black goats (Capra hircus coreanae) in the Republic of Korea

Jun Gu Kang; Yoon Kyoung Cho; Yong Sun Jo; Jeong Byoung Chae; Sung Suck Oh; Kye Hyung Kim; Mee Kyung Ko; Jongyoun Yi; Kyoung Seong Choi; Do Hyeon Yu; Hyeon Cheol Kim; Jinho Park; Bae Keun Park; Chang Yong Choi; Young Hun Jung; Joon Seok Chae

doi:10.1016/j.ttbdis.2018.04.018

Prevalence of severe fever with thrombocytopenia syndrome virus in black goats (Capra hircus coreanae) in the Republic of Korea

Jun Gu Kang, Yoon Kyoung Cho, Yong Sun Jo, Jeong Byoung Chae, Sung Suck Oh, Kye Hyung Kim, Mee Kyung Ko, Jongyoun Yi, Kyoung Seong Choi, Do Hyeon Yu, Hyeon Cheol Kim, Jinho Park, Bae Keun Park, Chang Yong Choi, Young Hun Jung, Joon Seok Chae

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Abstract

Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen in China, Japan, and the Republic of Korea (ROK). The aim of this study was to investigate the prevalence of SFTSV antigens and anti-SFTSV antibodies in black goats (Capra hircus coreanae) throughout the ROK. Sera were collected from 737 black goats in nine provinces in the ROK. Eighteen of 737 (2.4%) goat sera were positive for SFTSV on one-step reverse transcription nested polymerase chain reaction. The amplified 346-bp S segments of SFTSV sequences were classified into three genotypes (BG1, BG2, and BG3), and were included in the Japanese clade rather than the Chinese clade, based on phylogenetic analysis. Forty-three of 624 (6.9%) serum samples were seropositive for anti-SFTSV antibodies on enzyme-linked immunosorbent assay analysis. This study is the first to examine the molecular prevalence of SFTSV in goats and the first to perform serological detection of anti-SFTSV antibodies in livestock in the ROK. Moreover, the results indicate that SFTSV is widely distributed in goats and that additional monitoring for SFTSV is needed in livestock in the ROK.

Original language	English
Pages (from-to)	1153-1157
Number of pages	5
Journal	Ticks and Tick-borne Diseases
Volume	9
Issue number	5
DOIs	https://doi.org/10.1016/j.ttbdis.2018.04.018
State	Published - Jul 2018

Keywords

Goat
IFA
Prevalence
Republic of Korea
RT-PCR
Severe fever with thrombocytopenia syndrome virus

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ttbdis.2018.04.018

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Kang, J. G., Cho, Y. K., Jo, Y. S., Chae, J. B., Oh, S. S., Kim, K. H., Ko, M. K., Yi, J., Choi, K. S., Yu, D. H., Kim, H. C., Park, J., Park, B. K., Choi, C. Y., Jung, Y. H., & Chae, J. S. (2018). Prevalence of severe fever with thrombocytopenia syndrome virus in black goats (Capra hircus coreanae) in the Republic of Korea. Ticks and Tick-borne Diseases, 9(5), 1153-1157. https://doi.org/10.1016/j.ttbdis.2018.04.018

@article{c1b78dafa27146fea104c44b3b9a5a0f,

title = "Prevalence of severe fever with thrombocytopenia syndrome virus in black goats (Capra hircus coreanae) in the Republic of Korea",

abstract = "Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen in China, Japan, and the Republic of Korea (ROK). The aim of this study was to investigate the prevalence of SFTSV antigens and anti-SFTSV antibodies in black goats (Capra hircus coreanae) throughout the ROK. Sera were collected from 737 black goats in nine provinces in the ROK. Eighteen of 737 (2.4%) goat sera were positive for SFTSV on one-step reverse transcription nested polymerase chain reaction. The amplified 346-bp S segments of SFTSV sequences were classified into three genotypes (BG1, BG2, and BG3), and were included in the Japanese clade rather than the Chinese clade, based on phylogenetic analysis. Forty-three of 624 (6.9%) serum samples were seropositive for anti-SFTSV antibodies on enzyme-linked immunosorbent assay analysis. This study is the first to examine the molecular prevalence of SFTSV in goats and the first to perform serological detection of anti-SFTSV antibodies in livestock in the ROK. Moreover, the results indicate that SFTSV is widely distributed in goats and that additional monitoring for SFTSV is needed in livestock in the ROK.",

keywords = "Goat, IFA, Prevalence, Republic of Korea, RT-PCR, Severe fever with thrombocytopenia syndrome virus",

author = "Kang, {Jun Gu} and Cho, {Yoon Kyoung} and Jo, {Yong Sun} and Chae, {Jeong Byoung} and Oh, {Sung Suck} and Kim, {Kye Hyung} and Ko, {Mee Kyung} and Jongyoun Yi and Choi, {Kyoung Seong} and Yu, {Do Hyeon} and Kim, {Hyeon Cheol} and Jinho Park and Park, {Bae Keun} and Choi, {Chang Yong} and Jung, {Young Hun} and Chae, {Joon Seok}",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier GmbH",

year = "2018",

month = jul,

doi = "10.1016/j.ttbdis.2018.04.018",

language = "English",

volume = "9",

pages = "1153--1157",

journal = "Ticks and Tick-borne Diseases",

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Kang, JG, Cho, YK, Jo, YS, Chae, JB, Oh, SS, Kim, KH, Ko, MK, Yi, J, Choi, KS, Yu, DH, Kim, HC, Park, J, Park, BK, Choi, CY, Jung, YH & Chae, JS 2018, 'Prevalence of severe fever with thrombocytopenia syndrome virus in black goats (Capra hircus coreanae) in the Republic of Korea', Ticks and Tick-borne Diseases, vol. 9, no. 5, pp. 1153-1157. https://doi.org/10.1016/j.ttbdis.2018.04.018

TY - JOUR

T1 - Prevalence of severe fever with thrombocytopenia syndrome virus in black goats (Capra hircus coreanae) in the Republic of Korea

AU - Kang, Jun Gu

AU - Cho, Yoon Kyoung

AU - Jo, Yong Sun

AU - Chae, Jeong Byoung

AU - Oh, Sung Suck

AU - Kim, Kye Hyung

AU - Ko, Mee Kyung

AU - Yi, Jongyoun

AU - Choi, Kyoung Seong

AU - Yu, Do Hyeon

AU - Kim, Hyeon Cheol

AU - Park, Jinho

AU - Park, Bae Keun

AU - Choi, Chang Yong

AU - Jung, Young Hun

AU - Chae, Joon Seok

PY - 2018/7

Y1 - 2018/7

N2 - Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen in China, Japan, and the Republic of Korea (ROK). The aim of this study was to investigate the prevalence of SFTSV antigens and anti-SFTSV antibodies in black goats (Capra hircus coreanae) throughout the ROK. Sera were collected from 737 black goats in nine provinces in the ROK. Eighteen of 737 (2.4%) goat sera were positive for SFTSV on one-step reverse transcription nested polymerase chain reaction. The amplified 346-bp S segments of SFTSV sequences were classified into three genotypes (BG1, BG2, and BG3), and were included in the Japanese clade rather than the Chinese clade, based on phylogenetic analysis. Forty-three of 624 (6.9%) serum samples were seropositive for anti-SFTSV antibodies on enzyme-linked immunosorbent assay analysis. This study is the first to examine the molecular prevalence of SFTSV in goats and the first to perform serological detection of anti-SFTSV antibodies in livestock in the ROK. Moreover, the results indicate that SFTSV is widely distributed in goats and that additional monitoring for SFTSV is needed in livestock in the ROK.

AB - Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen in China, Japan, and the Republic of Korea (ROK). The aim of this study was to investigate the prevalence of SFTSV antigens and anti-SFTSV antibodies in black goats (Capra hircus coreanae) throughout the ROK. Sera were collected from 737 black goats in nine provinces in the ROK. Eighteen of 737 (2.4%) goat sera were positive for SFTSV on one-step reverse transcription nested polymerase chain reaction. The amplified 346-bp S segments of SFTSV sequences were classified into three genotypes (BG1, BG2, and BG3), and were included in the Japanese clade rather than the Chinese clade, based on phylogenetic analysis. Forty-three of 624 (6.9%) serum samples were seropositive for anti-SFTSV antibodies on enzyme-linked immunosorbent assay analysis. This study is the first to examine the molecular prevalence of SFTSV in goats and the first to perform serological detection of anti-SFTSV antibodies in livestock in the ROK. Moreover, the results indicate that SFTSV is widely distributed in goats and that additional monitoring for SFTSV is needed in livestock in the ROK.

KW - Goat

KW - IFA

KW - Prevalence

KW - Republic of Korea

KW - RT-PCR

KW - Severe fever with thrombocytopenia syndrome virus

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U2 - 10.1016/j.ttbdis.2018.04.018

DO - 10.1016/j.ttbdis.2018.04.018

M3 - Article

C2 - 29724620

AN - SCOPUS:85046349425

SN - 1877-959X

VL - 9

SP - 1153

EP - 1157

JO - Ticks and Tick-borne Diseases

JF - Ticks and Tick-borne Diseases

IS - 5

ER -

Prevalence of severe fever with thrombocytopenia syndrome virus in black goats (Capra hircus coreanae) in the Republic of Korea

Abstract

Keywords

UN SDGs

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