Production conditions for bruceanol B, an antibiotic that generates oxygen radical

Doseung Lee; Kyung Hwan Boo; Jin Kyu Woo; Gyeong Lyong Jeon; Jin Man Lee; Sang Han Lee; Jae Hoon Kim; Dong Sun Lee; Key Zung Riu

doi:10.3839/jksabc.2011.019

Production conditions for bruceanol B, an antibiotic that generates oxygen radical

Doseung Lee, Kyung Hwan Boo, Jin Kyu Woo, Gyeong Lyong Jeon, Jin Man Lee, Sang Han Lee, Jae Hoon Kim, Dong Sun Lee, Key Zung Riu

Research output: Contribution to journal › Article › peer-review

Abstract

Strain DS4, a soil microorganism producing an oxygen radical-generating antibacterial substance, bruceanol B, was isolated, and cultural conditions for the antibiotic production were optimized. Bruceanol B was separated by ethyl acetate extraction, silica gel and Sephadex LH-20 gel column chromatographies, and high-performance liquid chromatography (HPLC). The highest antibacterial activity was obtained from medium containing 1.5% soluble starch and 2.0% yeast extract, cultured at 30°C for 3.5 days.

Original language	English
Pages (from-to)	128-131
Number of pages	4
Journal	Journal of Applied Biological Chemistry
Volume	54
Issue number	1
DOIs	https://doi.org/10.3839/jksabc.2011.019
State	Published - 2011

Keywords

Bruceanol B
Production condition
Radical-generating antibiotic

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10.3839/jksabc.2011.019

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abstract = "Strain DS4, a soil microorganism producing an oxygen radical-generating antibacterial substance, bruceanol B, was isolated, and cultural conditions for the antibiotic production were optimized. Bruceanol B was separated by ethyl acetate extraction, silica gel and Sephadex LH-20 gel column chromatographies, and high-performance liquid chromatography (HPLC). The highest antibacterial activity was obtained from medium containing 1.5% soluble starch and 2.0% yeast extract, cultured at 30°C for 3.5 days.",

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author = "Doseung Lee and Boo, {Kyung Hwan} and Woo, {Jin Kyu} and Jeon, {Gyeong Lyong} and Lee, {Jin Man} and Lee, {Sang Han} and Kim, {Jae Hoon} and Lee, {Dong Sun} and Riu, {Key Zung}",

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doi = "10.3839/jksabc.2011.019",

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T1 - Production conditions for bruceanol B, an antibiotic that generates oxygen radical

AU - Lee, Doseung

AU - Boo, Kyung Hwan

AU - Woo, Jin Kyu

AU - Jeon, Gyeong Lyong

AU - Lee, Jin Man

AU - Lee, Sang Han

AU - Kim, Jae Hoon

AU - Lee, Dong Sun

AU - Riu, Key Zung

PY - 2011

Y1 - 2011

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AB - Strain DS4, a soil microorganism producing an oxygen radical-generating antibacterial substance, bruceanol B, was isolated, and cultural conditions for the antibiotic production were optimized. Bruceanol B was separated by ethyl acetate extraction, silica gel and Sephadex LH-20 gel column chromatographies, and high-performance liquid chromatography (HPLC). The highest antibacterial activity was obtained from medium containing 1.5% soluble starch and 2.0% yeast extract, cultured at 30°C for 3.5 days.

KW - Bruceanol B

KW - Production condition

KW - Radical-generating antibiotic

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DO - 10.3839/jksabc.2011.019

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VL - 54

SP - 128

EP - 131

JO - Journal of Applied Biological Chemistry

JF - Journal of Applied Biological Chemistry

IS - 1

ER -

Production conditions for bruceanol B, an antibiotic that generates oxygen radical

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Keywords

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