Abstract
Compound CBR004 which inhibits Ras farnesyl protein transferase, was produced by Bacillus licheniformis KCTC0372BP. Potassium phosphate and Tryptone were selected as media components for the production of CBR004 among 6 culture-variables using Plackett-Burman design. The yield of CBR004 was 0.99 g/l in a stirred fermenter at the C/N ratio of 1.87.
Original language | English |
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Pages (from-to) | 149-151 |
Number of pages | 3 |
Journal | Biotechnology Letters |
Volume | 20 |
Issue number | 2 |
DOIs | |
State | Published - 1998 |