Protective efficacy of a combined vaccine against Edwardsiella tarda, Streptococcus iniae and Streptococcus parauberis in farmed olive flounder Paralichthys olivaceu

Sang Yoon Han; Bo Kyu Kang; Bong Jo Kang; Jong Man Kim; Jee Eun Han; Ji Hyung Kim; Casiano Choresca; Sang Phil Shin; Jin Woo Jun; Se Chang Park

doi:10.3147/jsfp.46.108

Protective efficacy of a combined vaccine against Edwardsiella tarda, Streptococcus iniae and Streptococcus parauberis in farmed olive flounder Paralichthys olivaceu

Sang Yoon Han, Bo Kyu Kang, Bong Jo Kang, Jong Man Kim, Jee Eun Han, Ji Hyung Kim, Casiano Choresca, Sang Phil Shin, Jin Woo Jun, Se Chang Park

Department of Veterinary Medicine

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We evaluated the protective efficacy of a combined vaccine containing formalin-inactivated Edwardsiella tarda, Streptococcus iniae, and S. parauberis using olive flounder Paralichthys olivaceus. The fish were injected intraperitoneally with 0.1 mL of the combined vaccine. The fish were then challenged by intraperitoneal injection of the three bacterial strains. Mortality was significantly lower in the vaccinated groups compared with the control groups 3 wk post vaccination. Furthermore, there was a significant increase in antibody titer up to 16 wk after vaccination. Our results suggest that the combined vaccine successfully induced humoral and protective immunity against the three pathogens in olive flounder.

Original language	English
Pages (from-to)	108-111
Number of pages	4
Journal	Fish Pathology
Volume	46
Issue number	4
DOIs	https://doi.org/10.3147/jsfp.46.108
State	Published - 2011

Keywords

Combined vaccine
Edwardsiella tarda
Olive flounder
Protective efficacy
Streptococcus iniae
Streptococcus parauber

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3147/jsfp.46.108

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title = "Protective efficacy of a combined vaccine against Edwardsiella tarda, Streptococcus iniae and Streptococcus parauberis in farmed olive flounder Paralichthys olivaceu",

abstract = "We evaluated the protective efficacy of a combined vaccine containing formalin-inactivated Edwardsiella tarda, Streptococcus iniae, and S. parauberis using olive flounder Paralichthys olivaceus. The fish were injected intraperitoneally with 0.1 mL of the combined vaccine. The fish were then challenged by intraperitoneal injection of the three bacterial strains. Mortality was significantly lower in the vaccinated groups compared with the control groups 3 wk post vaccination. Furthermore, there was a significant increase in antibody titer up to 16 wk after vaccination. Our results suggest that the combined vaccine successfully induced humoral and protective immunity against the three pathogens in olive flounder.",

keywords = "Combined vaccine, Edwardsiella tarda, Olive flounder, Protective efficacy, Streptococcus iniae, Streptococcus parauber",

author = "Han, {Sang Yoon} and Kang, {Bo Kyu} and Kang, {Bong Jo} and Kim, {Jong Man} and Han, {Jee Eun} and Kim, {Ji Hyung} and Casiano Choresca and Shin, {Sang Phil} and Jun, {Jin Woo} and Park, {Se Chang}",

year = "2011",

doi = "10.3147/jsfp.46.108",

language = "English",

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pages = "108--111",

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AU - Han, Sang Yoon

AU - Kang, Bo Kyu

AU - Kang, Bong Jo

AU - Kim, Jong Man

AU - Han, Jee Eun

AU - Kim, Ji Hyung

AU - Choresca, Casiano

AU - Shin, Sang Phil

AU - Jun, Jin Woo

AU - Park, Se Chang

PY - 2011

Y1 - 2011

N2 - We evaluated the protective efficacy of a combined vaccine containing formalin-inactivated Edwardsiella tarda, Streptococcus iniae, and S. parauberis using olive flounder Paralichthys olivaceus. The fish were injected intraperitoneally with 0.1 mL of the combined vaccine. The fish were then challenged by intraperitoneal injection of the three bacterial strains. Mortality was significantly lower in the vaccinated groups compared with the control groups 3 wk post vaccination. Furthermore, there was a significant increase in antibody titer up to 16 wk after vaccination. Our results suggest that the combined vaccine successfully induced humoral and protective immunity against the three pathogens in olive flounder.

AB - We evaluated the protective efficacy of a combined vaccine containing formalin-inactivated Edwardsiella tarda, Streptococcus iniae, and S. parauberis using olive flounder Paralichthys olivaceus. The fish were injected intraperitoneally with 0.1 mL of the combined vaccine. The fish were then challenged by intraperitoneal injection of the three bacterial strains. Mortality was significantly lower in the vaccinated groups compared with the control groups 3 wk post vaccination. Furthermore, there was a significant increase in antibody titer up to 16 wk after vaccination. Our results suggest that the combined vaccine successfully induced humoral and protective immunity against the three pathogens in olive flounder.

KW - Combined vaccine

KW - Edwardsiella tarda

KW - Olive flounder

KW - Protective efficacy

KW - Streptococcus iniae

KW - Streptococcus parauber

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Protective efficacy of a combined vaccine against Edwardsiella tarda, Streptococcus iniae and Streptococcus parauberis in farmed olive flounder Paralichthys olivaceu

Abstract

Keywords

UN SDGs

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