Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities

Shukho Kim; Marzia Rahman; Sung Yong Seol; Sang Sun Yoon; Jungmin Kim

doi:10.1128/AEM.00648-12

Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities

Shukho Kim, Marzia Rahman, Sung Yong Seol, Sang Sun Yoon, Jungmin Kim

Department of Medicine

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1Ø has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.

Original language	English
Pages (from-to)	6380-6385
Number of pages	6
Journal	Applied and Environmental Microbiology
Volume	78
Issue number	17
DOIs	https://doi.org/10.1128/AEM.00648-12
State	Published - Sep 2012

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abstract = "We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1{\O} has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1{\O} may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.",

author = "Shukho Kim and Marzia Rahman and Seol, \{Sung Yong\} and Yoon, \{Sang Sun\} and Jungmin Kim",

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AU - Kim, Shukho

AU - Rahman, Marzia

AU - Seol, Sung Yong

AU - Yoon, Sang Sun

AU - Kim, Jungmin

PY - 2012/9

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AB - We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1Ø has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.

UR - https://www.scopus.com/pages/publications/84866155898

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DO - 10.1128/AEM.00648-12

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AN - SCOPUS:84866155898

SN - 0099-2240

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EP - 6385

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 17

ER -

Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities

Abstract

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