Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities

Shukho Kim; Marzia Rahman; Sung Yong Seol; Sang Sun Yoon; Jungmin Kim

doi:10.1128/AEM.00648-12

Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities

Shukho Kim
, Marzia Rahman
, Sung Yong Seol
, Sang Sun Yoon
, Jungmin Kim

Department of Medicine

Kyungpook National University
Brain Korea 21 Project for Medical Science
Yonsei University

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1Ø has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.

Original language	English
Pages (from-to)	6380-6385
Number of pages	6
Journal	Applied and Environmental Microbiology
Volume	78
Issue number	17
DOIs	https://doi.org/10.1128/AEM.00648-12
State	Published - Sep 2012

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abstract = "We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1{\O} has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1{\O} may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.",

author = "Shukho Kim and Marzia Rahman and Seol, \{Sung Yong\} and Yoon, \{Sang Sun\} and Jungmin Kim",

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AU - Kim, Shukho

AU - Rahman, Marzia

AU - Seol, Sung Yong

AU - Yoon, Sang Sun

AU - Kim, Jungmin

PY - 2012/9

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AB - We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1Ø has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.

UR - https://www.scopus.com/pages/publications/84866155898

U2 - 10.1128/AEM.00648-12

DO - 10.1128/AEM.00648-12

M3 - Article

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AN - SCOPUS:84866155898

SN - 0099-2240

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EP - 6385

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

IS - 17

ER -

Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities

Abstract

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