Quartz crystal microbalance (QCM) gravimetric sensing of theophylline via molecularly imprinted microporous polypyrrole copolymers

Jong Min Kim; Jin Chul Yang; Jin Young Park

doi:10.1016/j.snb.2014.09.047

Quartz crystal microbalance (QCM) gravimetric sensing of theophylline via molecularly imprinted microporous polypyrrole copolymers

Jong Min Kim, Jin Chul Yang, Jin Young Park

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

In this paper, we developed a novel molecularly imprinted conducting polymer (MICP) system consisting of porous poly(pyrrole-co-pyrrole-3-carboxylic acid) copolymer matrices for the recognition of theophylline (THEO), a drug molecule. Various porous MICP (p-MICP) films were made using colloidal lithography and examined via gravimetric technique [e.g. gold quartz crystal microbalances (QCMs)]. They showed faster sensing response than a planar MICP film due to the increased THEO binding sites obtained from porous structures. Thus, this lithographical approach to MICP sensors can enable the rebind of a specific template to be increased to achieve improved sensor capacity.

Original language	English
Pages (from-to)	50-55
Number of pages	6
Journal	Sensors and Actuators, B: Chemical
Volume	206
DOIs	https://doi.org/10.1016/j.snb.2014.09.047
State	Published - Jan 2015

Keywords

Colloidal lithography
Cyclic voltammetry
Molecularly imprinted conducting polymer (MICP)
Polystyrene colloids
Porous structure
Theophylline

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10.1016/j.snb.2014.09.047

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title = "Quartz crystal microbalance (QCM) gravimetric sensing of theophylline via molecularly imprinted microporous polypyrrole copolymers",

abstract = "In this paper, we developed a novel molecularly imprinted conducting polymer (MICP) system consisting of porous poly(pyrrole-co-pyrrole-3-carboxylic acid) copolymer matrices for the recognition of theophylline (THEO), a drug molecule. Various porous MICP (p-MICP) films were made using colloidal lithography and examined via gravimetric technique [e.g. gold quartz crystal microbalances (QCMs)]. They showed faster sensing response than a planar MICP film due to the increased THEO binding sites obtained from porous structures. Thus, this lithographical approach to MICP sensors can enable the rebind of a specific template to be increased to achieve improved sensor capacity.",

keywords = "Colloidal lithography, Cyclic voltammetry, Molecularly imprinted conducting polymer (MICP), Polystyrene colloids, Porous structure, Theophylline",

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AU - Kim, Jong Min

AU - Yang, Jin Chul

AU - Park, Jin Young

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AB - In this paper, we developed a novel molecularly imprinted conducting polymer (MICP) system consisting of porous poly(pyrrole-co-pyrrole-3-carboxylic acid) copolymer matrices for the recognition of theophylline (THEO), a drug molecule. Various porous MICP (p-MICP) films were made using colloidal lithography and examined via gravimetric technique [e.g. gold quartz crystal microbalances (QCMs)]. They showed faster sensing response than a planar MICP film due to the increased THEO binding sites obtained from porous structures. Thus, this lithographical approach to MICP sensors can enable the rebind of a specific template to be increased to achieve improved sensor capacity.

KW - Colloidal lithography

KW - Cyclic voltammetry

KW - Molecularly imprinted conducting polymer (MICP)

KW - Polystyrene colloids

KW - Porous structure

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JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

ER -

Quartz crystal microbalance (QCM) gravimetric sensing of theophylline via molecularly imprinted microporous polypyrrole copolymers

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Keywords

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