Recent research trend of biosensors for colorectal cancer specific protein biomarkers

Jingjing Li, Yunpei Si, Hye Jin Lee

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

Colorectal cancer (CRC) is one of the most prevalent diseases in modern society, constituting a serious threat to global health. Currently, routine clinical screening and early removal of precancerous polyps are the most successful methods for reducing CRC incidence and mortality. However, the high cost and invasive detection of sigmoidoscopy and colonoscopy limited the CRC-screening participation and prevention. The emergence of biosensors provides an inexpensive, sensitive, less invasive tool for detecting CRC disease biomarkers. This review highlights some of recent efforts made on developing biosensors with electrochemical and optical techniques targeting CRC specific protein biomarkers for early diagnosis and prognosis, potential applications, and future perspectives.

Original languageEnglish
Pages (from-to)253-259
Number of pages7
JournalApplied Chemistry for Engineering
Volume32
Issue number3
DOIs
StatePublished - 2021

Keywords

  • Biosensors
  • Colorectal cancer
  • Electrochemical methods
  • Optical techniques
  • Protein biomarkers

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