Recent research trends in voltammetric sensing platforms for hormones and their applications to human serum analyses

Yunpei Si, Jingjing Li, Sung Hwa Jhung, Hye Jin Lee

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

Hormones are essential chemical messengers that modulate body homeostasis and regulate appetite, mood, reproduction, and metabolism in the human body. Its dysregulation in the body can cause diabetes, Alzheimer's disease, and autism. The detection of hormone levels in biological fluids, including serum samples, could facilitate the precaution, diagnosis, and cure of diseases. Voltammetric sensing devices exhibiting significant sensitivity, selectivity, as well as facile, cost-effective fabrication, are one of the promising methods for detecting hormone levels. Thus, this review briefly highlights recent advances toward developing voltammetric sensors for a wide spectrum of amino acid-derived, peptide, and lipid-derived hormones alongside their applications to the analyses of human serum samples. Furthermore, several challenging issues and the prospects of voltammetric hormone-sensing devices in clinical diagnostic applications are discussed. Graphical abstract: [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)11-21
Number of pages11
JournalAnalytical Sciences
Volume38
Issue number1
DOIs
StatePublished - Jan 2022

Keywords

  • Aptamer
  • Disease diagnosis
  • Hormone
  • Human serum
  • Immunoassay
  • Sensor
  • Voltammetry

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