Research trend of biochip sensors for biomarkers specific to diagnostics of lung cancer diseases

Sang Hyuk Lee, Eunseo Goh, Hye Jin Lee

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Lung cancer has the highest death rate of any cancer diseases in Koreans. However, patients often feel difficult to recognize their disease before facing the terminal diagnosis due to the absence of any significant symptoms. Furthermore, the clear detection of an early cancer stage is usually obscure with existing diagnostic methods. For this reason, extensive research efforts have been made on introducing a wide range of biochemical diagnostic tools for the molecular level analysis of biological fluids for lung cancer diagnoses. A chip-based biosensor, one type of the analytical devices, can be a great potential for the diagnosis, which can be used without any further expensive analytical equipments nor skilled analysts. In this mini review, we highlight recent research trends on searching biomarker candidates and bio-chip sensors for lung cancer diagnosis in addition to discussing their future aspects.

Original languageEnglish
Pages (from-to)645-651
Number of pages7
JournalApplied Chemistry for Engineering
Volume29
Issue number6
DOIs
StatePublished - Dec 2018

Keywords

  • Biochip sensors
  • Blood biomarker
  • Electrochemical biosensor
  • Lateral flow immunoassay
  • Lung cancer disease
  • Optical biosensor

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