Risk factors for bone loss in patients having clinical conditions that restrict physical activity

Purpose: The purpose of this study was to identify the effect of sleep duration, depression, and other factors on the risk for low bone mineral density (BMD) in patients having physical restrictions due to chronic obstructive pulmonary disease, cardiovascular disease, stroke, or asthma. Design: A cross-sectional survey. Methods: The 2008-2011 Korea National Health and Nutrition Examination Survey assesses sociodemographic, physiological, and behavioral factors, including depression and sleep duration. The records of 512 individuals were examined in the present survey. Findings: Among men, absence of a depressive mood was associated with greater lumbar spine BMD, and among women, adequate sleep duration was associated with greater lumbar spine BMD. Conclusions: This study of individuals having restricted physical activity due to a respiratory or circulatory problem indicated that men without depression and women with adequate sleep had greater BMD. Clinical Relevance: Interventions that improve sleep duration and provide a stable psychological state may help to prevent declines of BMD in this population.