Ruthenium-catalyzed cross-coupling reactions between ketones and primary amines

Chan Sik Cho

doi:10.1016/j.catcom.2006.05.005

Ruthenium-catalyzed cross-coupling reactions between ketones and primary amines

Chan Sik Cho

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Ketones react with primary amines in dioxane at 180 °C in the presence of a catalytic amount of a ruthenium catalyst to give the corresponding α-alkylated ketones in moderate to good yields. With alkyl(methyl) ketones, the alkylation takes place exclusively at less-hindered methyl position over α-methylene.

Original language	English
Pages (from-to)	1012-1014
Number of pages	3
Journal	Catalysis Communications
Volume	7
Issue number	12
DOIs	https://doi.org/10.1016/j.catcom.2006.05.005
State	Published - Dec 2006

Keywords

α-Alkylation
Cross-coupling
Ketones
Primary amines
Ruthenium catalyst

Access to Document

10.1016/j.catcom.2006.05.005

Cite this

@article{9eb28874c72f42e6b57ef2422fd1b32b,

title = "Ruthenium-catalyzed cross-coupling reactions between ketones and primary amines",

abstract = "Ketones react with primary amines in dioxane at 180 °C in the presence of a catalytic amount of a ruthenium catalyst to give the corresponding α-alkylated ketones in moderate to good yields. With alkyl(methyl) ketones, the alkylation takes place exclusively at less-hindered methyl position over α-methylene.",

keywords = "α-Alkylation, Cross-coupling, Ketones, Primary amines, Ruthenium catalyst",

author = "Cho, {Chan Sik}",

year = "2006",

month = dec,

doi = "10.1016/j.catcom.2006.05.005",

language = "English",

volume = "7",

pages = "1012--1014",

journal = "Catalysis Communications",

issn = "1566-7367",

publisher = "Elsevier B.V.",

number = "12",

}

TY - JOUR

T1 - Ruthenium-catalyzed cross-coupling reactions between ketones and primary amines

AU - Cho, Chan Sik

PY - 2006/12

Y1 - 2006/12

N2 - Ketones react with primary amines in dioxane at 180 °C in the presence of a catalytic amount of a ruthenium catalyst to give the corresponding α-alkylated ketones in moderate to good yields. With alkyl(methyl) ketones, the alkylation takes place exclusively at less-hindered methyl position over α-methylene.

AB - Ketones react with primary amines in dioxane at 180 °C in the presence of a catalytic amount of a ruthenium catalyst to give the corresponding α-alkylated ketones in moderate to good yields. With alkyl(methyl) ketones, the alkylation takes place exclusively at less-hindered methyl position over α-methylene.

KW - α-Alkylation

KW - Cross-coupling

KW - Ketones

KW - Primary amines

KW - Ruthenium catalyst

UR - http://www.scopus.com/inward/record.url?scp=33750086014&partnerID=8YFLogxK

U2 - 10.1016/j.catcom.2006.05.005

DO - 10.1016/j.catcom.2006.05.005

M3 - Article

AN - SCOPUS:33750086014

SN - 1566-7367

VL - 7

SP - 1012

EP - 1014

JO - Catalysis Communications

JF - Catalysis Communications

IS - 12

ER -

Ruthenium-catalyzed cross-coupling reactions between ketones and primary amines

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this