Ruthenium-catalyzed regioselective α-alkylation of ketones with primary alcohols

Chan Sik Cho; Bok Tae Kim; Tae Jeong Kim; Sang Chul Shim

doi:10.1016/S0040-4039(02)01625-8

Ruthenium-catalyzed regioselective α-alkylation of ketones with primary alcohols

Chan Sik Cho
, Bok Tae Kim
, Tae Jeong Kim
, Sang Chul Shim

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

174 Scopus citations

Abstract

Ketones are regioselectively alkylated with an array of primary alcohols in dioxane at 80°C in the presence of a catalytic amount of a ruthenium catalyst together with KOH and a hydrogen acceptor.

Original language	English
Pages (from-to)	7987-7989
Number of pages	3
Journal	Tetrahedron Letters
Volume	43
Issue number	44
DOIs	https://doi.org/10.1016/S0040-4039(02)01625-8
State	Published - 28 Oct 2002

Keywords

Alkylation
Ketones
Primary alcohols
Ruthenium catalyst

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10.1016/S0040-4039(02)01625-8

Cite this

@article{a71f777e3add4772822cea27c51cf81f,

title = "Ruthenium-catalyzed regioselective α-alkylation of ketones with primary alcohols",

abstract = "Ketones are regioselectively alkylated with an array of primary alcohols in dioxane at 80°C in the presence of a catalytic amount of a ruthenium catalyst together with KOH and a hydrogen acceptor.",

keywords = "Alkylation, Ketones, Primary alcohols, Ruthenium catalyst",

author = "Cho, \{Chan Sik\} and Kim, \{Bok Tae\} and Kim, \{Tae Jeong\} and \{Chul Shim\}, Sang",

year = "2002",

month = oct,

day = "28",

doi = "10.1016/S0040-4039(02)01625-8",

language = "English",

volume = "43",

pages = "7987--7989",

journal = "Tetrahedron Letters",

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publisher = "Elsevier Ltd.",

number = "44",

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TY - JOUR

T1 - Ruthenium-catalyzed regioselective α-alkylation of ketones with primary alcohols

AU - Cho, Chan Sik

AU - Kim, Bok Tae

AU - Kim, Tae Jeong

AU - Chul Shim, Sang

PY - 2002/10/28

Y1 - 2002/10/28

N2 - Ketones are regioselectively alkylated with an array of primary alcohols in dioxane at 80°C in the presence of a catalytic amount of a ruthenium catalyst together with KOH and a hydrogen acceptor.

AB - Ketones are regioselectively alkylated with an array of primary alcohols in dioxane at 80°C in the presence of a catalytic amount of a ruthenium catalyst together with KOH and a hydrogen acceptor.

KW - Alkylation

KW - Ketones

KW - Primary alcohols

KW - Ruthenium catalyst

UR - https://www.scopus.com/pages/publications/0037190865

U2 - 10.1016/S0040-4039(02)01625-8

DO - 10.1016/S0040-4039(02)01625-8

M3 - Article

AN - SCOPUS:0037190865

SN - 0040-4039

VL - 43

SP - 7987

EP - 7989

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 44

ER -

Ruthenium-catalyzed regioselective α-alkylation of ketones with primary alcohols

Abstract

Keywords

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