Ruthenium-catalyzed synthesis of indoles from anilines and trialkanolammonium chlorides in an aqueous medium

Chan Sik Cho, Jin Hwang Kim, Sang Chul Shim

Research output: Contribution to journalArticlepeer-review

75 Scopus citations

Abstract

Anilines react with trialkanolammonium chlorides in an aqueous medium (H2O-dioxane) at 180°C in the presence of a catalytic amount of ruthenium(III) chloride hydrate and triphenylphosphine together with tin(II) chloride dihydrate to afford the corresponding indoles in good yields. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)1811-1814
Number of pages4
JournalTetrahedron Letters
Volume41
Issue number11
DOIs
StatePublished - 11 Mar 2000

Keywords

  • Catalyst
  • Cyclization
  • Indoles
  • Ruthenium

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