Significance of decreasing rate of HIV and HBV co-infection in a nationwide Korean HIV/AIDS cohort

Yoonjung Kim; Shin Woo Kim; Ki Tae Kwon; Hyun Ha Chang; Yoonhee Jun; Jang Wook Sohn; Dae Won Park; Joon Young Song; Jun Yong Choi; Hyo Youl Kim; June Myung Kim; Bo Youl Choi; Yunsu Choi; Mee Kyung Kee; Myeong Su Yoo; Jung Gyu Lee

doi:10.3346/jkms.2020.35.e7

Significance of decreasing rate of HIV and HBV co-infection in a nationwide Korean HIV/AIDS cohort

Yoonjung Kim, Shin Woo Kim, Ki Tae Kwon, Hyun Ha Chang, Yoonhee Jun, Jang Wook Sohn, Dae Won Park, Joon Young Song, Jun Yong Choi, Hyo Youl Kim, June Myung Kim, Bo Youl Choi, Yunsu Choi, Mee Kyung Kee, Myeong Su Yoo, Jung Gyu Lee

Department of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

From December 2006 to December 2016, 1093 human immunodeficiency virus (HIV) individuals < 70 years enrolled in Korea human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) cohort were analyzed to investigate the prevalence of HIV/HBV co-infection rate and hepatitis B virus surface antibody (HBsAb) positive rate based on birth year. The HBV co-infection prevalence rate was the highest (8.8%) in patients born between 1960 and 1964 and the lowest (0%) among those born between 1995 and 1999. A decreasing linear trend of HBV co-infection rate was observed according to the 5-year interval changes. HBsAb-positive rate was only 58.1% in our study. The national HBV vaccination programs have effectively lowered the HBV co-infection rate in HIV population. However, it is identified that the HIV population has low HBsAb positive rate. Further evidences supporting efficacy of booster immunization for HBsAb negative HIV patients are required and efforts should be made to increase HBsAb positive rates among HIV patients to prevent horizontal transmission.

Original language	English
Article number	e7
Journal	Journal of Korean Medical Science
Volume	35
Issue number	3
DOIs	https://doi.org/10.3346/jkms.2020.35.e7
State	Published - 20 Jan 2020

Keywords

Co-infection
HIV infection
Hepatitis B virus
National cohort
Vaccination

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3346/jkms.2020.35.e7

Cite this

Kim, Y., Kim, S. W., Kwon, K. T., Chang, H. H., Jun, Y., Sohn, J. W., Park, D. W., Song, J. Y., Choi, J. Y., Kim, H. Y., Kim, J. M., Choi, B. Y., Choi, Y., Kee, M. K., Yoo, M. S., & Lee, J. G. (2020). Significance of decreasing rate of HIV and HBV co-infection in a nationwide Korean HIV/AIDS cohort. Journal of Korean Medical Science, 35(3), Article e7. https://doi.org/10.3346/jkms.2020.35.e7

@article{debcf9a4c5c0445581ef7aabb0b17517,

title = "Significance of decreasing rate of HIV and HBV co-infection in a nationwide Korean HIV/AIDS cohort",

abstract = "From December 2006 to December 2016, 1093 human immunodeficiency virus (HIV) individuals < 70 years enrolled in Korea human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) cohort were analyzed to investigate the prevalence of HIV/HBV co-infection rate and hepatitis B virus surface antibody (HBsAb) positive rate based on birth year. The HBV co-infection prevalence rate was the highest (8.8%) in patients born between 1960 and 1964 and the lowest (0%) among those born between 1995 and 1999. A decreasing linear trend of HBV co-infection rate was observed according to the 5-year interval changes. HBsAb-positive rate was only 58.1% in our study. The national HBV vaccination programs have effectively lowered the HBV co-infection rate in HIV population. However, it is identified that the HIV population has low HBsAb positive rate. Further evidences supporting efficacy of booster immunization for HBsAb negative HIV patients are required and efforts should be made to increase HBsAb positive rates among HIV patients to prevent horizontal transmission.",

keywords = "Co-infection, HIV infection, Hepatitis B virus, National cohort, Vaccination",

author = "Yoonjung Kim and Kim, {Shin Woo} and Kwon, {Ki Tae} and Chang, {Hyun Ha} and Yoonhee Jun and Sohn, {Jang Wook} and Park, {Dae Won} and Song, {Joon Young} and Choi, {Jun Yong} and Kim, {Hyo Youl} and Kim, {June Myung} and Choi, {Bo Youl} and Yunsu Choi and Kee, {Mee Kyung} and Yoo, {Myeong Su} and Lee, {Jung Gyu}",

note = "Publisher Copyright: {\textcopyright} 2020 The Korean Academy of Medical Sciences.",

year = "2020",

month = jan,

day = "20",

doi = "10.3346/jkms.2020.35.e7",

language = "English",

volume = "35",

journal = "Journal of Korean Medical Science",

issn = "1011-8934",

publisher = "Korean Academy of Medical Science",

number = "3",

}

TY - JOUR

T1 - Significance of decreasing rate of HIV and HBV co-infection in a nationwide Korean HIV/AIDS cohort

AU - Kim, Yoonjung

AU - Kim, Shin Woo

AU - Kwon, Ki Tae

AU - Chang, Hyun Ha

AU - Jun, Yoonhee

AU - Sohn, Jang Wook

AU - Park, Dae Won

AU - Song, Joon Young

AU - Choi, Jun Yong

AU - Kim, Hyo Youl

AU - Kim, June Myung

AU - Choi, Bo Youl

AU - Choi, Yunsu

AU - Kee, Mee Kyung

AU - Yoo, Myeong Su

AU - Lee, Jung Gyu

PY - 2020/1/20

Y1 - 2020/1/20

N2 - From December 2006 to December 2016, 1093 human immunodeficiency virus (HIV) individuals < 70 years enrolled in Korea human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) cohort were analyzed to investigate the prevalence of HIV/HBV co-infection rate and hepatitis B virus surface antibody (HBsAb) positive rate based on birth year. The HBV co-infection prevalence rate was the highest (8.8%) in patients born between 1960 and 1964 and the lowest (0%) among those born between 1995 and 1999. A decreasing linear trend of HBV co-infection rate was observed according to the 5-year interval changes. HBsAb-positive rate was only 58.1% in our study. The national HBV vaccination programs have effectively lowered the HBV co-infection rate in HIV population. However, it is identified that the HIV population has low HBsAb positive rate. Further evidences supporting efficacy of booster immunization for HBsAb negative HIV patients are required and efforts should be made to increase HBsAb positive rates among HIV patients to prevent horizontal transmission.

AB - From December 2006 to December 2016, 1093 human immunodeficiency virus (HIV) individuals < 70 years enrolled in Korea human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) cohort were analyzed to investigate the prevalence of HIV/HBV co-infection rate and hepatitis B virus surface antibody (HBsAb) positive rate based on birth year. The HBV co-infection prevalence rate was the highest (8.8%) in patients born between 1960 and 1964 and the lowest (0%) among those born between 1995 and 1999. A decreasing linear trend of HBV co-infection rate was observed according to the 5-year interval changes. HBsAb-positive rate was only 58.1% in our study. The national HBV vaccination programs have effectively lowered the HBV co-infection rate in HIV population. However, it is identified that the HIV population has low HBsAb positive rate. Further evidences supporting efficacy of booster immunization for HBsAb negative HIV patients are required and efforts should be made to increase HBsAb positive rates among HIV patients to prevent horizontal transmission.

KW - Co-infection

KW - HIV infection

KW - Hepatitis B virus

KW - National cohort

KW - Vaccination

UR - http://www.scopus.com/inward/record.url?scp=85077942139&partnerID=8YFLogxK

U2 - 10.3346/jkms.2020.35.e7

DO - 10.3346/jkms.2020.35.e7

M3 - Article

C2 - 31950774

AN - SCOPUS:85077942139

SN - 1011-8934

VL - 35

JO - Journal of Korean Medical Science

JF - Journal of Korean Medical Science

IS - 3

M1 - e7

ER -

Significance of decreasing rate of HIV and HBV co-infection in a nationwide Korean HIV/AIDS cohort

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this