Abstract
Tufted angioma is a rare slowly progressive vascular tumor, characterized by histopathologic findings of numerous angiomatous lobules of "cannonball" appearance within the dermis. It affects children but occurs infrequently at birth. It appears as a clinical imitator of hemangioma of infancy (HOI), so it needs to be differentiated from HOI. Clinically, lesions most often present as red to purple, indurated or nodular plaque, and are usually located on the neck, upper trunk or proximal limb. We report six cases of tufted angioma of congenital onset. We undertook immunohistochemical study using CD31, D2-40 and GLUT1 to rule out other vascular tumors or malformations, particularly HOI. These cases may demonstrate the keys of differential diagnosis between HOI and tufted angioma, which share common features clinically and rarely histopathologically.
Original language | English |
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Pages (from-to) | 272-277 |
Number of pages | 6 |
Journal | Korean Journal of Dermatology |
Volume | 46 |
Issue number | 2 |
State | Published - Feb 2008 |
Keywords
- Congenital tufted angioma
- Differential diagnosis
- Hemangioma of infancy