Strain-controlled release of molecules from arrayed microcapsules supported on an elastomer substrate

Dong Choon Hyun, Geon Dae Moon, Choo Jin Park, Bong Soo Kim, Younan Xia, Unyong Jeong

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Performing under strain: Microcapsules arrayed on an elastomer substrate pumped out preloaded molecules upon mechanical stretching of the substrate as a result of a decrease in microcapsule volume. This technology could be applied to drug release, for example, from a flexible patch containing the drug through mechanical stimulation by opening and closing of the hand (see picture).

Original languageEnglish
Pages (from-to)724-727
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number3
DOIs
StatePublished - 17 Jan 2011

Keywords

  • drug delivery
  • microarrays
  • microcapsules
  • strain response

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