Strain-controlled release of molecules from arrayed microcapsules supported on an elastomer substrate

Dong Choon Hyun; Geon Dae Moon; Choo Jin Park; Bong Soo Kim; Younan Xia; Unyong Jeong

doi:10.1002/anie.201004838

Strain-controlled release of molecules from arrayed microcapsules supported on an elastomer substrate

Dong Choon Hyun
, Geon Dae Moon
, Choo Jin Park
, Bong Soo Kim
, Younan Xia
, Unyong Jeong

Yonsei University

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

Performing under strain: Microcapsules arrayed on an elastomer substrate pumped out preloaded molecules upon mechanical stretching of the substrate as a result of a decrease in microcapsule volume. This technology could be applied to drug release, for example, from a flexible patch containing the drug through mechanical stimulation by opening and closing of the hand (see picture).

Original language	English
Pages (from-to)	724-727
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	3
DOIs	https://doi.org/10.1002/anie.201004838
State	Published - 17 Jan 2011

Keywords

drug delivery
microarrays
microcapsules
strain response

Access to Document

10.1002/anie.201004838

Cite this

@article{697e025348274b33950ee422cb76b307,

title = "Strain-controlled release of molecules from arrayed microcapsules supported on an elastomer substrate",

abstract = "Performing under strain: Microcapsules arrayed on an elastomer substrate pumped out preloaded molecules upon mechanical stretching of the substrate as a result of a decrease in microcapsule volume. This technology could be applied to drug release, for example, from a flexible patch containing the drug through mechanical stimulation by opening and closing of the hand (see picture).",

keywords = "drug delivery, microarrays, microcapsules, strain response",

author = "Hyun, \{Dong Choon\} and Moon, \{Geon Dae\} and Park, \{Choo Jin\} and Kim, \{Bong Soo\} and Younan Xia and Unyong Jeong",

year = "2011",

month = jan,

day = "17",

doi = "10.1002/anie.201004838",

language = "English",

volume = "50",

pages = "724--727",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "3",

}

TY - JOUR

T1 - Strain-controlled release of molecules from arrayed microcapsules supported on an elastomer substrate

AU - Hyun, Dong Choon

AU - Moon, Geon Dae

AU - Park, Choo Jin

AU - Kim, Bong Soo

AU - Xia, Younan

AU - Jeong, Unyong

PY - 2011/1/17

Y1 - 2011/1/17

N2 - Performing under strain: Microcapsules arrayed on an elastomer substrate pumped out preloaded molecules upon mechanical stretching of the substrate as a result of a decrease in microcapsule volume. This technology could be applied to drug release, for example, from a flexible patch containing the drug through mechanical stimulation by opening and closing of the hand (see picture).

AB - Performing under strain: Microcapsules arrayed on an elastomer substrate pumped out preloaded molecules upon mechanical stretching of the substrate as a result of a decrease in microcapsule volume. This technology could be applied to drug release, for example, from a flexible patch containing the drug through mechanical stimulation by opening and closing of the hand (see picture).

KW - drug delivery

KW - microarrays

KW - microcapsules

KW - strain response

UR - https://www.scopus.com/pages/publications/78651404470

U2 - 10.1002/anie.201004838

DO - 10.1002/anie.201004838

M3 - Article

C2 - 21226163

AN - SCOPUS:78651404470

SN - 1433-7851

VL - 50

SP - 724

EP - 727

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 3

ER -

Strain-controlled release of molecules from arrayed microcapsules supported on an elastomer substrate

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this