Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications

Jin Hwan Chung; Young Kyung Kim; Kyo Han Kim; Tae Yub Kwon; Seyede Ziba Vaezmomeni; Mohammad Samiei; Marzyeh Aghazadeh; Soodabeh Davaran; Mehrdad Mahkam; Ghale Asadi; Abolfazl Akbarzadeh

doi:10.3109/21691401.2014.944644

Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications

Jin Hwan Chung, Young Kyung Kim, Kyo Han Kim, Tae Yub Kwon, Seyede Ziba Vaezmomeni, Mohammad Samiei, Marzyeh Aghazadeh, Soodabeh Davaran, Mehrdad Mahkam, Ghale Asadi, Abolfazl Akbarzadeh

Department of Dentistry

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Hydroxyapatite (HA), the main mineral component of bones and teeth, was synthesized by using the reaction between calcium nitrate tetrahydrate Ca(NO₃)₂·4H₂O and diammonium hydrogen phosphate (NH₄)₂HPO₄ (DAHP) with a chemical precipitation method. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. HA is an inorganic component (75% w) and chitosan, alginate and albumin (Egg white) are organic components of nanocomposites (25% w). Nanocomposites were prepared in deionized water solutions, at room temperature, using a mechanical and magnetic stirrer for 48 h. The microstructure and morphology of sintered n-HAP were tested at different preheating temperature and laser sintering speed with scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).

Original language	English
Pages (from-to)	277-284
Number of pages	8
Journal	Artificial Cells, Nanomedicine and Biotechnology
Volume	44
Issue number	1
DOIs	https://doi.org/10.3109/21691401.2014.944644
State	Published - 1 Jan 2016

Keywords

Biomedical applications
Hydroxyapatite
Inorganic-organic nanocomposite
Natural polymers

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Chung, J. H., Kim, Y. K., Kim, K. H., Kwon, T. Y., Vaezmomeni, S. Z., Samiei, M., Aghazadeh, M., Davaran, S., Mahkam, M., Asadi, G., & Akbarzadeh, A. (2016). Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications. Artificial Cells, Nanomedicine and Biotechnology, 44(1), 277-284. https://doi.org/10.3109/21691401.2014.944644

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title = "Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications",

abstract = "Hydroxyapatite (HA), the main mineral component of bones and teeth, was synthesized by using the reaction between calcium nitrate tetrahydrate Ca(NO3)2·4H2O and diammonium hydrogen phosphate (NH4)2HPO4 (DAHP) with a chemical precipitation method. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. HA is an inorganic component (75% w) and chitosan, alginate and albumin (Egg white) are organic components of nanocomposites (25% w). Nanocomposites were prepared in deionized water solutions, at room temperature, using a mechanical and magnetic stirrer for 48 h. The microstructure and morphology of sintered n-HAP were tested at different preheating temperature and laser sintering speed with scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).",

keywords = "Biomedical applications, Hydroxyapatite, Inorganic-organic nanocomposite, Natural polymers",

author = "Chung, {Jin Hwan} and Kim, {Young Kyung} and Kim, {Kyo Han} and Kwon, {Tae Yub} and Vaezmomeni, {Seyede Ziba} and Mohammad Samiei and Marzyeh Aghazadeh and Soodabeh Davaran and Mehrdad Mahkam and Ghale Asadi and Abolfazl Akbarzadeh",

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doi = "10.3109/21691401.2014.944644",

language = "English",

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pages = "277--284",

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Chung, JH, Kim, YK, Kim, KH, Kwon, TY, Vaezmomeni, SZ, Samiei, M, Aghazadeh, M, Davaran, S, Mahkam, M, Asadi, G & Akbarzadeh, A 2016, 'Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications', Artificial Cells, Nanomedicine and Biotechnology, vol. 44, no. 1, pp. 277-284. https://doi.org/10.3109/21691401.2014.944644

TY - JOUR

T1 - Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications

AU - Chung, Jin Hwan

AU - Kim, Young Kyung

AU - Kim, Kyo Han

AU - Kwon, Tae Yub

AU - Vaezmomeni, Seyede Ziba

AU - Samiei, Mohammad

AU - Aghazadeh, Marzyeh

AU - Davaran, Soodabeh

AU - Mahkam, Mehrdad

AU - Asadi, Ghale

AU - Akbarzadeh, Abolfazl

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Hydroxyapatite (HA), the main mineral component of bones and teeth, was synthesized by using the reaction between calcium nitrate tetrahydrate Ca(NO3)2·4H2O and diammonium hydrogen phosphate (NH4)2HPO4 (DAHP) with a chemical precipitation method. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. HA is an inorganic component (75% w) and chitosan, alginate and albumin (Egg white) are organic components of nanocomposites (25% w). Nanocomposites were prepared in deionized water solutions, at room temperature, using a mechanical and magnetic stirrer for 48 h. The microstructure and morphology of sintered n-HAP were tested at different preheating temperature and laser sintering speed with scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).

AB - Hydroxyapatite (HA), the main mineral component of bones and teeth, was synthesized by using the reaction between calcium nitrate tetrahydrate Ca(NO3)2·4H2O and diammonium hydrogen phosphate (NH4)2HPO4 (DAHP) with a chemical precipitation method. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. HA is an inorganic component (75% w) and chitosan, alginate and albumin (Egg white) are organic components of nanocomposites (25% w). Nanocomposites were prepared in deionized water solutions, at room temperature, using a mechanical and magnetic stirrer for 48 h. The microstructure and morphology of sintered n-HAP were tested at different preheating temperature and laser sintering speed with scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).

KW - Biomedical applications

KW - Hydroxyapatite

KW - Inorganic-organic nanocomposite

KW - Natural polymers

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SN - 2169-1401

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JO - Artificial Cells, Nanomedicine and Biotechnology

JF - Artificial Cells, Nanomedicine and Biotechnology

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ER -

Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications

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Keywords

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