Synthesis of 3-Alkenylisoindolin-1-ones via Palladium(0)-Catalyzed Coupling and Cyclization between 2-Iodobenzoyl Chloride and Aldimines

Chan Sik Cho, Xue Wu, Li Hong Jiang, Sang Chul Shim, Heung Jin Choi, Tae Jeong Kim

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

2-Iodobenzoyl chloride reacts with aldimines in acetonitrile at 100° under carbon monoxide in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride together with triethylamine to give the corresponding 3-alkenylisoindolin-1-ones in good yields.

Original languageEnglish
Pages (from-to)265-268
Number of pages4
JournalJournal of Heterocyclic Chemistry
Volume35
Issue number1
DOIs
StatePublished - 1998

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