Synthesis of 3-phenoxy-1,3-dihydro-1-isobenzofuranones by palladium-catalyzed carbonylative cyclization of 2- bromobenzaldehyde with phenols

Chan Sik Cho, Dong Yeol Baek, Sang Chul Shim

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Abstract

2-Bromobenzaldehyde reacts with phenols in acetonitrile under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride to afford the corresponding 3-phenoxy-1,3-dihydro-1-isobenzofuranones in high yields.

Original languageEnglish
Pages (from-to)1101-1104
Number of pages4
JournalJournal of Heterocyclic Chemistry
Volume36
Issue number4
DOIs
StatePublished - 1999

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