Synthesis of 6 H -Isoindolo[2,1- a ]indol-6-ones via Palladium-Catalyzed Carbonylative Cyclization of 2-(2-Bromophenyl)-1 H -indoles

Jae Myeong Yoo; Son Long Ho; Chan Sik Cho

doi:10.1055/s-0035-1561560

Synthesis of 6 H -Isoindolo[2,1- a ]indol-6-ones via Palladium-Catalyzed Carbonylative Cyclization of 2-(2-Bromophenyl)-1 H -indoles

Jae Myeong Yoo, Son Long Ho, Chan Sik Cho

Department of Applied Chemistry

Kyungpook National University

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

2-(2-Bromophenyl)-1H-indoles are carbonylatively cyclized under carbon monoxide pressure in toluene in the presence of a catalytic amount of PdCl₂ and PPh₃ along with a base to give 6H-isoindolo[2,1-a]indol-6-ones in high yields.

Original language	English
Article number	st-2015-u0930-l
Pages (from-to)	1383-1386
Number of pages	4
Journal	Synlett
Volume	27
Issue number	9
DOIs	https://doi.org/10.1055/s-0035-1561560
State	Published - 2 Jun 2016

Keywords

carbonylation
catalysis
cyclization
heterocycles
indolones

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title = "Synthesis of 6 H -Isoindolo[2,1- a ]indol-6-ones via Palladium-Catalyzed Carbonylative Cyclization of 2-(2-Bromophenyl)-1 H -indoles",

abstract = "2-(2-Bromophenyl)-1H-indoles are carbonylatively cyclized under carbon monoxide pressure in toluene in the presence of a catalytic amount of PdCl2 and PPh3 along with a base to give 6H-isoindolo[2,1-a]indol-6-ones in high yields.",

keywords = "carbonylation, catalysis, cyclization, heterocycles, indolones",

author = "Yoo, {Jae Myeong} and Ho, {Son Long} and Cho, {Chan Sik}",

note = "Publisher Copyright: {\textcopyright} Georg Thieme Verlag Stuttgart. New York.",

year = "2016",

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doi = "10.1055/s-0035-1561560",

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T1 - Synthesis of 6 H -Isoindolo[2,1- a ]indol-6-ones via Palladium-Catalyzed Carbonylative Cyclization of 2-(2-Bromophenyl)-1 H -indoles

AU - Yoo, Jae Myeong

AU - Ho, Son Long

AU - Cho, Chan Sik

N1 - Publisher Copyright: © Georg Thieme Verlag Stuttgart. New York.

PY - 2016/6/2

Y1 - 2016/6/2

N2 - 2-(2-Bromophenyl)-1H-indoles are carbonylatively cyclized under carbon monoxide pressure in toluene in the presence of a catalytic amount of PdCl2 and PPh3 along with a base to give 6H-isoindolo[2,1-a]indol-6-ones in high yields.

AB - 2-(2-Bromophenyl)-1H-indoles are carbonylatively cyclized under carbon monoxide pressure in toluene in the presence of a catalytic amount of PdCl2 and PPh3 along with a base to give 6H-isoindolo[2,1-a]indol-6-ones in high yields.

KW - carbonylation

KW - catalysis

KW - cyclization

KW - heterocycles

KW - indolones

UR - http://www.scopus.com/inward/record.url?scp=84957641256&partnerID=8YFLogxK

U2 - 10.1055/s-0035-1561560

DO - 10.1055/s-0035-1561560

M3 - Article

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SN - 0936-5214

VL - 27

SP - 1383

EP - 1386

JO - Synlett

JF - Synlett

IS - 9

M1 - st-2015-u0930-l

ER -

Synthesis of 6 H -Isoindolo[2,1- a ]indol-6-ones via Palladium-Catalyzed Carbonylative Cyclization of 2-(2-Bromophenyl)-1 H -indoles

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Keywords

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