Synthesis of high surface area mesoporous bioactive glass nanospheres

Hui suk Yun; Sang hyun Kim; Soyoung Lee; In hyuck Song

doi:10.1016/j.matlet.2010.04.053

Synthesis of high surface area mesoporous bioactive glass nanospheres

Hui suk Yun, Sang hyun Kim, Soyoung Lee, In hyuck Song

Korea Institute of Materials Science

Research output: Contribution to journal › Article › peer-review

65 Scopus citations

Abstract

Mesoporous bioactive glass (MBG) nanospheres having the composition of SiO₂-CaO-P₂O₅ with both a large specific surface area (∼ 1040 m² g^{- 1}) and pore volume (1.54 cm³ g^{- 1}) were prepared using the ionic surfactant, cetyltrimethyl-ammonium bromide (CTAB), as a template. The size of the nanospheres depends on the amount of CaO that is incorporated and can be controlled over the range of diameters from 20 to 200 nm under dilute aqueous condition. In vitro bioactivity studies were carried out in simulated body fluid (SBF). Cytotoxicity tests of the MBG nanospheres were also performed by observing their influence on J774 macrophages at various concentrations.

Original language	English
Pages (from-to)	1850-1853
Number of pages	4
Journal	Materials Letters
Volume	64
Issue number	16
DOIs	https://doi.org/10.1016/j.matlet.2010.04.053
State	Published - 31 Aug 2010

Keywords

Bioactive glass
Ceramics
Mesoporous
Nanomaterials

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10.1016/j.matlet.2010.04.053

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title = "Synthesis of high surface area mesoporous bioactive glass nanospheres",

abstract = "Mesoporous bioactive glass (MBG) nanospheres having the composition of SiO2-CaO-P2O5 with both a large specific surface area (∼ 1040 m2 g- 1) and pore volume (1.54 cm3 g- 1) were prepared using the ionic surfactant, cetyltrimethyl-ammonium bromide (CTAB), as a template. The size of the nanospheres depends on the amount of CaO that is incorporated and can be controlled over the range of diameters from 20 to 200 nm under dilute aqueous condition. In vitro bioactivity studies were carried out in simulated body fluid (SBF). Cytotoxicity tests of the MBG nanospheres were also performed by observing their influence on J774 macrophages at various concentrations.",

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doi = "10.1016/j.matlet.2010.04.053",

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T1 - Synthesis of high surface area mesoporous bioactive glass nanospheres

AU - Yun, Hui suk

AU - Kim, Sang hyun

AU - Lee, Soyoung

AU - Song, In hyuck

PY - 2010/8/31

Y1 - 2010/8/31

N2 - Mesoporous bioactive glass (MBG) nanospheres having the composition of SiO2-CaO-P2O5 with both a large specific surface area (∼ 1040 m2 g- 1) and pore volume (1.54 cm3 g- 1) were prepared using the ionic surfactant, cetyltrimethyl-ammonium bromide (CTAB), as a template. The size of the nanospheres depends on the amount of CaO that is incorporated and can be controlled over the range of diameters from 20 to 200 nm under dilute aqueous condition. In vitro bioactivity studies were carried out in simulated body fluid (SBF). Cytotoxicity tests of the MBG nanospheres were also performed by observing their influence on J774 macrophages at various concentrations.

AB - Mesoporous bioactive glass (MBG) nanospheres having the composition of SiO2-CaO-P2O5 with both a large specific surface area (∼ 1040 m2 g- 1) and pore volume (1.54 cm3 g- 1) were prepared using the ionic surfactant, cetyltrimethyl-ammonium bromide (CTAB), as a template. The size of the nanospheres depends on the amount of CaO that is incorporated and can be controlled over the range of diameters from 20 to 200 nm under dilute aqueous condition. In vitro bioactivity studies were carried out in simulated body fluid (SBF). Cytotoxicity tests of the MBG nanospheres were also performed by observing their influence on J774 macrophages at various concentrations.

KW - Bioactive glass

KW - Ceramics

KW - Mesoporous

KW - Nanomaterials

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DO - 10.1016/j.matlet.2010.04.053

M3 - Article

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VL - 64

SP - 1850

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JO - Materials Letters

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Synthesis of high surface area mesoporous bioactive glass nanospheres

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Keywords

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