Synthesis of isoindolin-1-ones via palladium-catalyzed intermolecular coupling and heteroannulation between 2-iodobenzoyl chloride and imines

Chan Sik Cho; Hyung Sup Shim; Heung Jin Choi; Tae Jeong Kim; Sang Chul Shim; Myung Chul Kim

doi:10.1016/S0040-4039(00)00495-0

Synthesis of isoindolin-1-ones via palladium-catalyzed intermolecular coupling and heteroannulation between 2-iodobenzoyl chloride and imines

Chan Sik Cho, Hyung Sup Shim, Heung Jin Choi, Tae Jeong Kim, Sang Chul Shim, Myung Chul Kim

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

2-Iodobenzoyl chloride reacts with an array of imines in acetonitrile- methanol under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride/triphenylphosphine together with triethylamine to afford the corresponding isoindolin-1-ones in moderate yields. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	3891-3893
Number of pages	3
Journal	Tetrahedron Letters
Volume	41
Issue number	20
DOIs	https://doi.org/10.1016/S0040-4039(00)00495-0
State	Published - 21 May 2000

Keywords

Catalyst
Cyclization
Isoindolin-1-ones
Palladium

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10.1016/S0040-4039(00)00495-0

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title = "Synthesis of isoindolin-1-ones via palladium-catalyzed intermolecular coupling and heteroannulation between 2-iodobenzoyl chloride and imines",

abstract = "2-Iodobenzoyl chloride reacts with an array of imines in acetonitrile- methanol under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride/triphenylphosphine together with triethylamine to afford the corresponding isoindolin-1-ones in moderate yields. (C) 2000 Elsevier Science Ltd.",

keywords = "Catalyst, Cyclization, Isoindolin-1-ones, Palladium",

author = "Cho, {Chan Sik} and Shim, {Hyung Sup} and Choi, {Heung Jin} and Kim, {Tae Jeong} and Shim, {Sang Chul} and Kim, {Myung Chul}",

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doi = "10.1016/S0040-4039(00)00495-0",

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T1 - Synthesis of isoindolin-1-ones via palladium-catalyzed intermolecular coupling and heteroannulation between 2-iodobenzoyl chloride and imines

AU - Cho, Chan Sik

AU - Shim, Hyung Sup

AU - Choi, Heung Jin

AU - Kim, Tae Jeong

AU - Shim, Sang Chul

AU - Kim, Myung Chul

PY - 2000/5/21

Y1 - 2000/5/21

N2 - 2-Iodobenzoyl chloride reacts with an array of imines in acetonitrile- methanol under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride/triphenylphosphine together with triethylamine to afford the corresponding isoindolin-1-ones in moderate yields. (C) 2000 Elsevier Science Ltd.

AB - 2-Iodobenzoyl chloride reacts with an array of imines in acetonitrile- methanol under carbon monoxide pressure in the presence of a catalytic amount of bis(triphenylphosphine)palladium(II) chloride/triphenylphosphine together with triethylamine to afford the corresponding isoindolin-1-ones in moderate yields. (C) 2000 Elsevier Science Ltd.

KW - Catalyst

KW - Cyclization

KW - Isoindolin-1-ones

KW - Palladium

UR - http://www.scopus.com/inward/record.url?scp=0000516896&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)00495-0

DO - 10.1016/S0040-4039(00)00495-0

M3 - Article

AN - SCOPUS:0000516896

SN - 0040-4039

VL - 41

SP - 3891

EP - 3893

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 20

ER -

Synthesis of isoindolin-1-ones via palladium-catalyzed intermolecular coupling and heteroannulation between 2-iodobenzoyl chloride and imines

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Keywords

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