Synthesis of spiroisoindolinones by palladium-catalyzed heterocyclization of 2-iodobenzoyl chloride with ketimines

Chan Sik Cho, Xue Wu, Li Hong Jiang, Sang Chul Shim, Hong Rak Kim

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

2-Iodobenzoyl chloride reacts with ketimines in acetonitrile at 100°under carbon monoxide pressure in the presence of a catalytic amount of a palladium catalyst together with triethylamine to afford the corresponding spiroisoindolinones in high yields.

Original languageEnglish
Pages (from-to)297-300
Number of pages4
JournalJournal of Heterocyclic Chemistry
Volume36
Issue number1
DOIs
StatePublished - 1999

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