Synthetic hydrogel as an implant material with enhanced biocompatibility and biostability

J. H. Choi, B. H. Park, Y. A. Han, J. O. Lim

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The poly(2-hydroxyethyl methacrylate) (PHEMA) and copolymer hydrogels with increased mechanical strength and water content were prepared using hydrophilic comonomer, sodium methacrylate (SMA), at high monomer concentration. The investigation of cytotoxicity, cell adhesion and in vivo tissue reaction of the synthesized PHEMA and P(HEMA-co-SMA) hydrogels was also discussed. The PHEMA hydrogels were synthesized by free radical polymerization of HEMA and ethylene glycol dimethacrylate (EGDMA) in water. The biocompatibility of the PHEMA and P(HEMA-co-SMA) hydrogels was examined. It was shown that the growth and metabolism of cell for biomaterials depend upon the hydrophilic/hydrophobic character of the comonomers and chemical structure of hydrogels.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages1588
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period17/05/0421/05/04

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