The anti-thrombotic activity of surfactins

Jong Hwan Lim; Byung Kwon Park; Myoung Seok Kim; Mi Hyun Hwang; Man Hee Rhee; Seung Chun Park; Hyo In Yun

doi:10.4142/jvs.2005.6.4.353

The anti-thrombotic activity of surfactins

Jong Hwan Lim, Byung Kwon Park, Myoung Seok Kim, Mi Hyun Hwang, Man Hee Rhee, Seung Chun Park, Hyo In Yun

Department of Veterinary Medicine

Chungnam National University

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner. Our findings suggest that surfactins are able to prevent a platelet aggregation leading to an inhibition of additional fibrin clot formation, and to enhance fibrinolysis with facilitated diffusion of fibrinolytic agents.

Original language	English
Pages (from-to)	353-355
Number of pages	3
Journal	Journal of Veterinary Science
Volume	6
Issue number	4
DOIs	https://doi.org/10.4142/jvs.2005.6.4.353
State	Published - Dec 2005

Keywords

Anti-platelet aggregation
Platelet rich plasma
Surfactins

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10.4142/jvs.2005.6.4.353

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abstract = "Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner. Our findings suggest that surfactins are able to prevent a platelet aggregation leading to an inhibition of additional fibrin clot formation, and to enhance fibrinolysis with facilitated diffusion of fibrinolytic agents.",

keywords = "Anti-platelet aggregation, Platelet rich plasma, Surfactins",

author = "Lim, \{Jong Hwan\} and Park, \{Byung Kwon\} and Kim, \{Myoung Seok\} and Hwang, \{Mi Hyun\} and Rhee, \{Man Hee\} and Park, \{Seung Chun\} and Yun, \{Hyo In\}",

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AU - Lim, Jong Hwan

AU - Park, Byung Kwon

AU - Kim, Myoung Seok

AU - Hwang, Mi Hyun

AU - Rhee, Man Hee

AU - Park, Seung Chun

AU - Yun, Hyo In

PY - 2005/12

Y1 - 2005/12

N2 - Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner. Our findings suggest that surfactins are able to prevent a platelet aggregation leading to an inhibition of additional fibrin clot formation, and to enhance fibrinolysis with facilitated diffusion of fibrinolytic agents.

AB - Platelet aggregation was inhibited and the density of platelet-rich plasma (PRP) clots was decreased by the preincubation of PRP with surfactins, an acidic lipopeptide of Bacillus subtilis complex BC1212 isolated from soybean paste, in dose-dependent manner. Our findings suggest that surfactins are able to prevent a platelet aggregation leading to an inhibition of additional fibrin clot formation, and to enhance fibrinolysis with facilitated diffusion of fibrinolytic agents.

KW - Anti-platelet aggregation

KW - Platelet rich plasma

KW - Surfactins

UR - https://www.scopus.com/pages/publications/31144459460

U2 - 10.4142/jvs.2005.6.4.353

DO - 10.4142/jvs.2005.6.4.353

M3 - Article

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AN - SCOPUS:31144459460

SN - 1229-845X

VL - 6

SP - 353

EP - 355

JO - Journal of Veterinary Science

JF - Journal of Veterinary Science

IS - 4

ER -

The anti-thrombotic activity of surfactins

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Keywords

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