The effect of intraperitoneal ropivacaine on pain after laparoscopic colectomy: A prospective randomized controlled trial

Yong Hee Park, Hyun Kang, Young Cheol Woo, Sun Gyoo Park, Chong Wha Baek, Yong Hun Jung, Jin Yun Kim, Gill Hoi Koo, Seong Deok Kim, Jun Seok Park

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34 Scopus citations

Abstract

Background: Although laparoscopic procedures are becoming more common, postoperative pain remains a major factor causing delayed patient recovery. There have been several trials to reduce pain by instilling local anesthetics into the peritoneal cavity, but there has been no study on prolonged (∼300 min) or intensive surgery. We investigated the analgesic effect of intraperitoneal ropivacaine instillation after laparoscopic colectomy. Materials and Methods: Sixty patients were randomized to three groups. Twenty patients in each group received 50 mL of appropriate solutions after the formation of a pneumoperitoneum. The solution was normal saline (control) in group C and 1 mg/kg of ropivacaine in each of groups I and D. In group D, ropivacaine was sprayed again before the elimination of the pneumoperitoneum. Patients reported their postoperative pain using a subjective visual analogue scale. Fentanyl use for pain relief and frequency of pushing a button (FPB) for a bolus of patient controlled analgesia were evaluated, and scales of recovery rates were obtained. Results: The immediate postoperative pain score was lower in groups I and D than in group C. In groups I and D, FPB measures and fentanyl use were both less than in group C. The time taken to resume a regular diet was shorter in group D than in group C. Conclusions: The intraperitoneal instillation of ropivacaine was effective in reducing postoperative pain and in shortening the recovery course after laparoscopic colectomy. The additional instillation of ropivacaine at the end of the surgery proved even more effective.

Original languageEnglish
Pages (from-to)94-100
Number of pages7
JournalJournal of Surgical Research
Volume171
Issue number1
DOIs
StatePublished - Nov 2011

Keywords

  • intraperitoneal local anesthesia
  • laparoscopic colectomy
  • postoperative pain
  • ropivacaine

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