Abstract
The aim of this study is to fabricate scaffolds from two types of biodegradable materials using a precision deposition system that we developed. The precision deposition system, which is one of rapid prototyping(RP) methods, uses technology that enables the manufacture of three-dimensional microstructures. Fabrication of 3D tissue engineering scaffolds using the precision deposition system required the combination of several technologies, including motion control, thermal control, pneumatic control, computer-aided design and computer-aided manufacturing( CAD/CAM) software. Through the fabrication and human bone marrow mesenchymal stem cells(hBMSCs) proliferation experiments of two kinds of scaffolds using poly(ε-caprolactone)(PCL) and poly(lactic-co-glycolic acid)(PLGA), feasibility of application to the tissue engineering of precision deposition system is demonstrated.
Original language | English |
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Pages (from-to) | 506-511 |
Number of pages | 6 |
Journal | Tissue Engineering and Regenerative Medicine |
Volume | 5 |
Issue number | 3 |
State | Published - Sep 2008 |
Keywords
- Precision deposition system
- Rapid prototyping
- Scaffold
- Tissue engineering